PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2526812-9 1989 In the presence of N-methyl-1-deoxynojirimycin, an inhibitor of glucosidase I, 30-40% of the newly synthesized molecules appeared at the cell surface, and half-time for appearance of this pool was identical to that found in control cells. N-methyldeoxynojirimycin 19-46 mannosyl-oligosaccharide glucosidase Homo sapiens 64-77 2532008-2 1989 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin, both inhibitors of glucosidases I and II, decreased intracellular TSH (to 60-76% of control) and secreted TSH (to 60-63% of control) after a 1-hour incubation (pulse) with [35S]methionine and an 8-hour incubation (chase) in isotope-free media. N-methyldeoxynojirimycin 23-50 mannosyl-oligosaccharide glucosidase Homo sapiens 71-92 1609840-6 1992 Treatment of cultured skin fibroblasts for 7 days with N-methyldeoxynojirimycin, a potent inhibitor of the endoplasmic reticulum processing enzymes glucosidase I and II, resulted in an accumulation of the same Man5GlcNAc2-PP-dolichol species that was elevated in juvenile NCL brain. N-methyldeoxynojirimycin 55-79 mannosyl-oligosaccharide glucosidase Homo sapiens 148-168 2965702-6 1988 In this study, we used two compounds that inhibit oligosaccharide processing at earlier steps: (i) N-methyl-1-deoxynojirimycin (MedJN), which inhibits glucosidases I and II and yields glucosylated, high mannose oligosaccharides, and (ii) manno-1-deoxynojirimycin (MandJN), which inhibits mannosidase I and yields high mannose oligosaccharides. N-methyldeoxynojirimycin 99-126 mannosyl-oligosaccharide glucosidase Homo sapiens 151-172 2965702-6 1988 In this study, we used two compounds that inhibit oligosaccharide processing at earlier steps: (i) N-methyl-1-deoxynojirimycin (MedJN), which inhibits glucosidases I and II and yields glucosylated, high mannose oligosaccharides, and (ii) manno-1-deoxynojirimycin (MandJN), which inhibits mannosidase I and yields high mannose oligosaccharides. N-methyldeoxynojirimycin 128-133 mannosyl-oligosaccharide glucosidase Homo sapiens 151-172