PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15233279-1 2004 We have developed a radiolabeled lipophilic acetylcholine analogue, N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) to measure brain acetylcholinesterase (AChE) activity by positron emission tomography (PET) in vivo. N-methylpiperidin-4-yl acetate 68-103 acetylcholinesterase (Cartwright blood group) Homo sapiens 155-159 11295884-0 2001 Positron emission tomographic measurement of brain acetylcholinesterase activity using N-[(11)C]methylpiperidin-4-yl acetate without arterial blood sampling: methodology of shape analysis and its diagnostic power for Alzheimer"s disease. N-methylpiperidin-4-yl acetate 87-124 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-71 11295884-1 2001 N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) is a radiotracer that has been used successfully for the quantitative measurement of acetylcholinesterase (AChE) activity in the human brain with positron emission tomography (PET) using a standard compartment model analysis and a metabolite-corrected arterial input function. N-methylpiperidin-4-yl acetate 0-35 acetylcholinesterase (Cartwright blood group) Homo sapiens 133-153 11295884-1 2001 N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) is a radiotracer that has been used successfully for the quantitative measurement of acetylcholinesterase (AChE) activity in the human brain with positron emission tomography (PET) using a standard compartment model analysis and a metabolite-corrected arterial input function. N-methylpiperidin-4-yl acetate 0-35 acetylcholinesterase (Cartwright blood group) Homo sapiens 155-159 15801847-1 2005 The reduction of acetylcholinesterase (AChE) activity in the brain has been measured in dementia disorders such as Alzheimer"s disease and dementia with Lewy bodies using (11)C-labeled acetylcholine analogues, N-[(11)C]methylpiperidin-4-yl acetate and propionate, and positron emission tomography (PET). N-methylpiperidin-4-yl acetate 210-247 acetylcholinesterase (Cartwright blood group) Homo sapiens 17-37 15801847-1 2005 The reduction of acetylcholinesterase (AChE) activity in the brain has been measured in dementia disorders such as Alzheimer"s disease and dementia with Lewy bodies using (11)C-labeled acetylcholine analogues, N-[(11)C]methylpiperidin-4-yl acetate and propionate, and positron emission tomography (PET). N-methylpiperidin-4-yl acetate 210-247 acetylcholinesterase (Cartwright blood group) Homo sapiens 39-43 12724174-2 2003 We measured brain acetylcholinesterase (AChE) activity in 54 patients with AD and in 22 normal controls by positron emission tomography and N-[(11)C]methylpiperidin-4-yl acetate to characterize the cholinergic pathology in AD. N-methylpiperidin-4-yl acetate 140-177 acetylcholinesterase (Cartwright blood group) Homo sapiens 40-44