PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21302359-6 2011 The newly synthesized TRH analogues were also evaluated in vivo to assess their potencies in antagonism of barbiturate-induced sleeping time, and several analogues displayed potent analeptic activity. barbituric acid 107-118 thyrotropin releasing hormone Mus musculus 22-25 817374-1 1975 Previous work has demonstrated that thyrotropin-releasing hormone (TRH) and its beta-alanine analogue (beta-ala TRH) are potent antagonists of barbiturate-induced sedation. barbituric acid 143-154 thyrotropin releasing hormone Mus musculus 36-65 20188155-4 2010 While [Glu(2)]TRH itself is analeptic, its co-administration with TRH into mice produced a dose-dependent attenuation of TRH-evoked reversal of barbiturate-induced sleeping time. barbituric acid 144-155 thyrotropin releasing hormone Mus musculus 14-17 20188155-4 2010 While [Glu(2)]TRH itself is analeptic, its co-administration with TRH into mice produced a dose-dependent attenuation of TRH-evoked reversal of barbiturate-induced sleeping time. barbituric acid 144-155 thyrotropin releasing hormone Mus musculus 66-69 20188155-4 2010 While [Glu(2)]TRH itself is analeptic, its co-administration with TRH into mice produced a dose-dependent attenuation of TRH-evoked reversal of barbiturate-induced sleeping time. barbituric acid 144-155 thyrotropin releasing hormone Mus musculus 66-69 817374-1 1975 Previous work has demonstrated that thyrotropin-releasing hormone (TRH) and its beta-alanine analogue (beta-ala TRH) are potent antagonists of barbiturate-induced sedation. barbituric acid 143-154 thyrotropin releasing hormone Mus musculus 67-70 817374-1 1975 Previous work has demonstrated that thyrotropin-releasing hormone (TRH) and its beta-alanine analogue (beta-ala TRH) are potent antagonists of barbiturate-induced sedation. barbituric acid 143-154 thyrotropin releasing hormone Mus musculus 112-115 817374-6 1975 Since phenobarbital treatment of grand mal epilepsy is often limited by sedation and since TRH antogonizes sedation and enhances anticonvulsant effects of the barbiturate, the hormone or a congener may find value as an adjunct in therapy. barbituric acid 159-170 thyrotropin releasing hormone Mus musculus 91-94