PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26708109-0 2016 Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARgamma activators. barbituric acid 39-54 peroxisome proliferator activated receptor gamma Homo sapiens 70-79 26708109-7 2016 The most significant finding of our study is that BA derivatives with symmetrically substituted weakly polar side chains result in the desired moderate level of PPARgamma binding affinities. barbituric acid 50-52 peroxisome proliferator activated receptor gamma Homo sapiens 161-170 21463618-0 2011 A novel agonist of PPAR-gamma based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. barbituric acid 39-54 peroxisome proliferator activated receptor gamma Homo sapiens 19-29 21463618-2 2011 Recently, a new series of PPARgamma ligands based on barbituric acid has been designed, in which 5-(4-(benzyloxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione (SKLB102) showed a high affinity with PPARgamma. barbituric acid 53-68 peroxisome proliferator activated receptor gamma Homo sapiens 26-35 21463618-2 2011 Recently, a new series of PPARgamma ligands based on barbituric acid has been designed, in which 5-(4-(benzyloxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione (SKLB102) showed a high affinity with PPARgamma. barbituric acid 53-68 peroxisome proliferator activated receptor gamma Homo sapiens 197-206