PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1511880-2 1992 This enzyme catalyses the conversion of DHO to orotic acid and plays a major role in the pyrimidine pathway, as DHO is the effector of the positive control of the transcription of at least four genes, URA1, URA3, URA4 and URA10. pyrimidine 89-99 orotate phosphoribosyltransferase URA10 Saccharomyces cerevisiae S288C 222-227