PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31255972-3 2019 Based on our previous studies, four pyrimidine-fused heterocycles (PFH) were selected as they revealed satisfactory inhibitory action against mammalian alpha-glucosidase. pyrimidine 36-46 sucrase-isomaltase Homo sapiens 152-169 23978663-0 2013 Synthesis of new pyrimidine-fused derivatives as potent and selective antidiabetic alpha-glucosidase inhibitors. pyrimidine 17-27 sucrase-isomaltase Homo sapiens 83-100 23978663-1 2013 The synthesis of a set of pyrimidine-fused derivatives (L1-L8), resulting from the incorporation of different fragments on the pyrimidine-fused heterocycle (PFH) of the earlier reported alpha-glucosidase (alpha-Gls) inhibitor (C1-C5), allowed the discovery of new ligands with modest and selective inhibitory activity. pyrimidine 26-36 sucrase-isomaltase Homo sapiens 186-203 23978663-1 2013 The synthesis of a set of pyrimidine-fused derivatives (L1-L8), resulting from the incorporation of different fragments on the pyrimidine-fused heterocycle (PFH) of the earlier reported alpha-glucosidase (alpha-Gls) inhibitor (C1-C5), allowed the discovery of new ligands with modest and selective inhibitory activity. pyrimidine 26-36 sucrase-isomaltase Homo sapiens 205-214 24028850-3 2013 Recently, pyrimidine fused heterocycles (PFHs) revealed inhibitory properties against alpha-glucosidase (alpha-Gls) which is an important target enzyme for those drugs playing significant role in treatment of type-II diabetes and HIV/AIDS infection. pyrimidine 10-20 sucrase-isomaltase Homo sapiens 86-103 24028850-3 2013 Recently, pyrimidine fused heterocycles (PFHs) revealed inhibitory properties against alpha-glucosidase (alpha-Gls) which is an important target enzyme for those drugs playing significant role in treatment of type-II diabetes and HIV/AIDS infection. pyrimidine 10-20 sucrase-isomaltase Homo sapiens 105-114