PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16828468-4	2006	pyr-1 encodes CAD, a trifunctional enzyme required for de novo pyrimidine synthesis, and pyr-1(cu8) mutants are rescued by supplying exogenous pyrimidines.	pyrimidine	63-73	Glutamine-dependent carbamoyl-phosphate synthase	Caenorhabditis elegans	0-5	
16828468-6	2006	rib-1 mutant lethality was enhanced in a pyr-1 mutant background, indicating that HSPG synthesis is very sensitive to decreased pyrimidine pools, and HS disaccharides are moderately decreased in both rib-1 and pyr-1 mutants.	pyrimidine	128-138	Glutamine-dependent carbamoyl-phosphate synthase	Caenorhabditis elegans	41-46	
20148972-8	2010	The effects of mutations in pyr-1, which encodes the enzyme catalyzing the first three steps of de novo pyrimidine biosynthesis, did not phenotypically resemble those of umps-1(-); instead, the synthetic lethality and enlargement of gut granules exhibited by the umps-1(-) mutant was suppressed by pyr-1(-).	pyrimidine	104-114	Glutamine-dependent carbamoyl-phosphate synthase	Caenorhabditis elegans	28-33