PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2192377-9 1990 In both rad1-1 rad6-1 and rad1-1 rad18-2 rad54-1 hosts, the mean fluence for one lethal event corresponds approximately to one pyrimidine dimer per plasmid molecule, indicating that they are absolute repairless hosts for incoming DNA. pyrimidine 127-137 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 8-14 2192377-9 1990 In both rad1-1 rad6-1 and rad1-1 rad18-2 rad54-1 hosts, the mean fluence for one lethal event corresponds approximately to one pyrimidine dimer per plasmid molecule, indicating that they are absolute repairless hosts for incoming DNA. pyrimidine 127-137 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 26-32 379625-0 1979 The mutagenic potential of unexcised pyrimidine dimers in Saccharomyces cerevisiae, rad1-1: evidence from photoreactivation and pedigree analysis. pyrimidine 37-47 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 84-90 6373364-1 1984 Cell-free extracts from wild-type yeast (RAD+) and from rad mutants belonging to the RAD3 epistatic group (rad1-1, rad2-1, rad3-1, rad4 -1) contain activities catalyzing the excision of pyrimidine dimers (PD) from purified ultraviolet-irradiated DNA which was not pre-treated with exogenous UV-endonuclease. pyrimidine 186-196 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 107-113 6352404-4 1983 Excision repair of pyrimidine dimers can occur during meiosis and the RAD1 gene product is required; alternate excision pathways do not exist. pyrimidine 19-29 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 70-74 6352404-5 1983 Although the rate of elongation is decreased, the presence of pyrimidine dimers during meiosis in the rad1-1 strain does not block meiotic DNA synthesis suggesting a bypass mechanism. pyrimidine 62-72 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 102-106 6352404-7 1983 Since pyrimidine dimers induced in parental strands of rad1-1 prior to premeiotic DNA synthesis do not become associated with newly synthesized DNA, the mechanism for replicational bypass does not appear to involve a recombinational process. pyrimidine 6-16 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 55-59 7012136-8 1981 These experiments suggest that the RAD1, RAD2, RAD3, RAD4 (and probably RAD14) genes are all required for the incision of UV-irradiated DNA during pyrimidine dimer excision in vivo. pyrimidine 147-157 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 35-39 379625-1 1979 Photoreactivation and pedigree analysis have been combined to show that unexcised pyrimidine dimers in the DNA of rad1-1 yeast can initiate mutagenesis after passing through several DNA replications. pyrimidine 82-92 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 115-121 775322-4 1976 Strains defective (rad 1-3) or with a reduced capacity (p-, cytoplasmic respiratory deficient mutants) in excision repair of ultraviolet-induced pyrimidine dimers show a greater sensitivity to formaldehyde than the corresponding wild type. pyrimidine 145-155 ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C 19-24