PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32779873-1 2021 Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is an important drug target in the one-carbon metabolic pathway, since its activity is critical for purine and pyrimidine biosynthesis. pyrimidine 167-177 serine hydroxymethyltransferase 2 Homo sapiens 14-47 32779873-1 2021 Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is an important drug target in the one-carbon metabolic pathway, since its activity is critical for purine and pyrimidine biosynthesis. pyrimidine 167-177 serine hydroxymethyltransferase 2 Homo sapiens 49-54 27530298-1 2016 The cytosolic and mitochondrial isoforms of serine hydroxymethyltransferase (SHMT1 and SHMT2, respectively) are well-recognized targets of cancer research, since their activity is critical for purine and pyrimidine biosynthesis and because of their prominent role in the metabolic reprogramming of cancer cells. pyrimidine 204-214 serine hydroxymethyltransferase 2 Homo sapiens 87-92