PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11035006-1	2001	A major control element of the human c-myc oncogene is the nuclease-hypersensitive purine/pyrimidine-rich sequence.	pyrimidine	90-100	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	37-42	
16317762-6	2006	It preferentially cleaves RNA in between the pyrimidine and purine dinucleotides UA, UG, and CA, at the coding region determinant (CRD) of c-myc RNA.	pyrimidine	45-55	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	139-144	
18628958-3	2008	METHODOLOGY/PRINCIPAL FINDINGS: Here, we report that the majority of genes in human purine and pyrimidine biosynthesis pathway were induced and directly bound by c-Myc in the P493-6 human Burkitt"s lymphoma model cell line.	pyrimidine	95-105	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	162-167	
8940139-2	1996	The THZif-1 protein bound specifically to the single-stranded (ss) pyrimidine-rich DNA of the NHE (ss c-myc NHE-C) with an apparent dissociation constant (Kd (app)) of 0.077 microM.	pyrimidine	67-77	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	102-107	
8831693-5	1996	Moreover, MAZi protein bound specifically to the pyrimidine-rich strand of the CT-element of the c-myc gene in vitro and strongly induced the expression of chloramphenicol acetyltransferase (CAT) from a c-myc promoter/ CAT reporter construct in human pancreatic cells.	pyrimidine	49-59	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	97-102	
8701093-16	1996	A specific DNA binding element in the promoter region of the c-myc proto-oncogene has been identified as AT-rich domain of homopurine/pyrimidine stretches flanked by GC-rich sequences.	pyrimidine	134-144	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	61-66	
8601634-2	1996	The ability of c-Myc to bind the sequence CAC(G/A)TG and transactivate appears to be linked to its transforming activity; however, c-Myc also represses transcription in vitro through a pyrimidine-rich cis element termed the initiator (Inr).	pyrimidine	185-195	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	15-20	
8601634-2	1996	The ability of c-Myc to bind the sequence CAC(G/A)TG and transactivate appears to be linked to its transforming activity; however, c-Myc also represses transcription in vitro through a pyrimidine-rich cis element termed the initiator (Inr).	pyrimidine	185-195	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	131-136	
28847964-8	2017	Moreover, inhibition of MYC target pyrimidine synthesis genes such as CAD, UMPS, and CTPS blocked cell growth, and thus are potential targets for colorectal cancer therapy.	pyrimidine	35-45	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	24-27	
7876260-1	1995	We have previously reported that heterogeneous nuclear ribonucleoprotein K (hnRNP K) binds to the pyrimidine-rich strand of the CT element found in the human c-myc gene and activates CT reporter-driven gene expression in vivo.	pyrimidine	98-108	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	158-163	
31113844-6	2019	RESULTS: In examining modulations within the pyrimidine pathway, we identified that the addition of DTX to cells treated with ADI-PEG20 resulted in translocation of stabilized c-Myc to the nucleus.	pyrimidine	45-55	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	176-181	
7794930-3	1995	The human c-myc protooncogene contains a 23 base pair purine-pyrimidine-rich motif (-62 to -40) within its predominant promoter, P2, that is a potential target for purine-purine-pyrimidine triplex formation.	pyrimidine	61-71	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	10-15	
7794930-3	1995	The human c-myc protooncogene contains a 23 base pair purine-pyrimidine-rich motif (-62 to -40) within its predominant promoter, P2, that is a potential target for purine-purine-pyrimidine triplex formation.	pyrimidine	178-188	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	10-15	
34009981-0	2021	Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins.	pyrimidine	29-39	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	90-93	
34009981-2	2021	Here, we describe the design and synthesis of a series of pyrimidine-based derivatives able to inhibit Aurora A kinase activity and reduce levels of cMYC and MYCN.	pyrimidine	58-68	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	149-153