PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7769843-7	1995	However, K562R displayed a significant (ie 70%) reduction in the level of activity of the pyrimidine salvage pathway enzyme, deoxycytidine kinase (dCK), compared to K562S cells.	pyrimidine	90-100	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	147-150	
9342227-1	1997	Deoxycytidine kinase (dCK) is a salvage pathway enzyme with broad substrate specificity that can phosphorylate both pyrimidine and purine deoxynucleosides, including important antiviral and cytostatic agents.	pyrimidine	116-126	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	22-25	
20810757-3	2010	RESULTS: Cells transduced with dCK mutant reporter genes showed high in vitro and in vivo uptake of pyrimidine-based radiopharmaceuticals ((18)F-FEAU) comparable to that of herpes simplex virus type-1 thymidine kinase (HSV1-tk)-transduced cells.	pyrimidine	100-110	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	31-34	
31383553-9	2019	INTERPRETATIONS: These data indicate that the cytosolic pyrimidine salvage pathway enzymes TK1 and dCK are critical for therapeutic efficacy of deoxynucleoside therapy for Tk2 deficiency.	pyrimidine	56-66	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	99-102	
20810757-6	2010	CONCLUSION: The mutants of human dCK can be used as pyrimidine-specific PET reporter genes for imaging with (18)F-FEAU during treatment with acycloguanosine-based antiviral drugs.	pyrimidine	52-62	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	33-36	
16533034-1	2006	Human deoxycytidine kinase (dCK) phosphorylates both pyrimidine and purine deoxynucleosides, including numerous nucleoside analogue prodrugs.	pyrimidine	53-63	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	28-31	
12429345-1	2002	Deoxycytidine kinase (dCK) is a salvage pathway enzyme that can phosphorylate both pyrimidine and purine deoxynucleosides, including important antiviral and cytostatic agents.	pyrimidine	83-93	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	22-25	
10387103-1	1999	Deoxycytidine kinase (dCK) is an enzyme with broad substrate specificity which can phosphorylate pyrimidine and purine deoxynucleosides, including important antiviral and cytostatic agents.	pyrimidine	97-107	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	22-25	
15561147-1	2004	Human deoxycytidine kinase (dCK) is a key enzyme in the 5"-phosphorylation of purine and pyrimidine deoxynucleosides with deoxycytidine as the most efficient substrate.	pyrimidine	89-99	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	28-31	
9845378-2	1998	Previous in vitro models have shown cross-resistance between the purine analog 2-chlorodeoxyadenosine (cladribine) and the pyrimidine analogs 2",2"-difluorodeoxycytidine (gemcitabine) and 1-beta-D-arabinofuranosylcytosine (cytosine arabinoside, cytarabine) with reduced deoxycytidine kinase (dCK) activity as the underlying determinant of resistance.	pyrimidine	123-133	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	292-295