PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7255197-2 1980 The method involves the use of kinetic secondary alpha-hydrogen isotope effects which are expected to accompany sp2 to sp3 rehybridization of C-6 of the pyrimidine ring if they occur prior to or at the rate determining step. pyrimidine 153-163 Sp3 transcription factor Homo sapiens 119-122