PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12558503-1 2003 The splicing factor U2AF(65), U2 small nuclear ribonucleoprotein particle (snRNP) auxillary factor of 65 kDa, binds to pyrimidine-rich sequences at 3" splice sites to recruit U2 snRNP to pre-mRNAs. pyrimidine 119-129 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 20-28 16809543-2 2006 The 65- and 35-kD subunits of the splicing factor U2AF, U2AF65 and U2AF35, recognize, respectively, the pyrimidine-rich tract and the conserved terminal AG present at metazoan 3" splice sites. pyrimidine 104-114 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 56-62 16809543-4 2006 DEK phosphorylated at serines 19 and 32 associates with U2AF35, facilitates the U2AF35-AG interaction and prevents binding of U2AF65 to pyrimidine tracts not followed by AG. pyrimidine 136-146 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 126-132 10691733-2 2000 Stimulation of pre-mRNA splicing by an adjacent cis-linked cleavage and polyadenylation site in HeLa cell nuclear extract is shown to occur at an early step in splicing, the binding of U2AF 65 to the pyrimidine tract of the intron 3" splice site. pyrimidine 200-210 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 185-192 31271494-4 2019 In addition, we show that the RS domain of U2AF65 drives a liquid-liquid phase separation that is amplified by intronic RNA with repeated pyrimidine tracts. pyrimidine 138-148 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 43-49 9303319-3 1997 Early in mammalian spliceosome assembly, U2AF65 binds to the pyrimidine tract between the BPS and AG. pyrimidine 61-71 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 41-47 9632785-7 1998 The site-specific pyrimidine tract binding activity of the U2AF heterodimer has previously been assigned to hU2AF65. pyrimidine 18-28 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 108-115 31271494-5 2019 In cells, knockdown of either U2AF65 or CAPERalpha improves the inclusion of cassette exons that are preceded by such repeated pyrimidine-rich motifs. pyrimidine 127-137 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 30-36 25422459-5 2014 Based on a comparison of new U2AF(65) structures bound to either A- or G-containing Py tracts with previously identified pyrimidine-containing structures, we expected to find that a D231V amino acid change in U2AF(65) would specify U over other nucleotides. pyrimidine 121-131 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 29-36 25422459-5 2014 Based on a comparison of new U2AF(65) structures bound to either A- or G-containing Py tracts with previously identified pyrimidine-containing structures, we expected to find that a D231V amino acid change in U2AF(65) would specify U over other nucleotides. pyrimidine 121-131 U2 small nuclear RNA auxiliary factor 2 Homo sapiens 209-216