PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10739924-1 2000 Crystals of the Saccharomyces cerevisiae pyrimidine biosynthetic enzyme orotidine 5"-phosphate decarboxylase (ODCase) were grown by the hanging-drop vapor-diffusion technique at 277 K using polyethylene glycol 4000 as the precipitant. pyrimidine 41-51 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 72-108 10739924-1 2000 Crystals of the Saccharomyces cerevisiae pyrimidine biosynthetic enzyme orotidine 5"-phosphate decarboxylase (ODCase) were grown by the hanging-drop vapor-diffusion technique at 277 K using polyethylene glycol 4000 as the precipitant. pyrimidine 41-51 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 110-116 9822821-6 1998 Finally, the expression of two pyrimidine biosynthesis genes URA1 and URA3 was found to be severely affected by bas1 and bas2 mutations in the absence of adenine, establishing a regulatory link between the two nucleotide biosynthesis pathways. pyrimidine 31-41 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 70-74 9185581-2 1997 This strategy is based on the ability of URA3 to complement mutations in pyrF, an Escherichia coli gene required for pyrimidine biosynthesis. pyrimidine 117-127 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 41-45 1511880-2 1992 This enzyme catalyses the conversion of DHO to orotic acid and plays a major role in the pyrimidine pathway, as DHO is the effector of the positive control of the transcription of at least four genes, URA1, URA3, URA4 and URA10. pyrimidine 89-99 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 207-211 2204810-1 1990 Expression of the yeast pyrimidine biosynthetic gene, URA3, is induced three- to fivefold in response to uracil starvation, and this regulation is mediated by the transcriptional activator PPR1 (pyrimidine pathway regulator 1). pyrimidine 24-34 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 54-58 2204810-1 1990 Expression of the yeast pyrimidine biosynthetic gene, URA3, is induced three- to fivefold in response to uracil starvation, and this regulation is mediated by the transcriptional activator PPR1 (pyrimidine pathway regulator 1). pyrimidine 195-205 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 54-58