PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33872670-4 2021 Deletion mutants that mimic cleaved PGAM5 existed not only in the cytosol but also in the nucleus, and a fraction of cleaved PGAM5 translocated to the nucleus during mitophagy induced by the uncoupler CCCP. Carbonyl Cyanide m-Chlorophenyl Hydrazone 201-205 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 125-130 29438981-5 2018 Mitochondrial stress triggered by carbonyl cyanide m-chlorophenyl hydrazone (CCCP) treatment led to cytosolic release of endogenous Pgam5 and subsequent dephosphorylation of beta-catenin, which was strongly diminished in Pgam5 and PARL knockout cells. Carbonyl Cyanide m-Chlorophenyl Hydrazone 34-75 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 132-137 29438981-5 2018 Mitochondrial stress triggered by carbonyl cyanide m-chlorophenyl hydrazone (CCCP) treatment led to cytosolic release of endogenous Pgam5 and subsequent dephosphorylation of beta-catenin, which was strongly diminished in Pgam5 and PARL knockout cells. Carbonyl Cyanide m-Chlorophenyl Hydrazone 34-75 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 221-226 29438981-5 2018 Mitochondrial stress triggered by carbonyl cyanide m-chlorophenyl hydrazone (CCCP) treatment led to cytosolic release of endogenous Pgam5 and subsequent dephosphorylation of beta-catenin, which was strongly diminished in Pgam5 and PARL knockout cells. Carbonyl Cyanide m-Chlorophenyl Hydrazone 77-81 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 132-137 29438981-5 2018 Mitochondrial stress triggered by carbonyl cyanide m-chlorophenyl hydrazone (CCCP) treatment led to cytosolic release of endogenous Pgam5 and subsequent dephosphorylation of beta-catenin, which was strongly diminished in Pgam5 and PARL knockout cells. Carbonyl Cyanide m-Chlorophenyl Hydrazone 77-81 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 221-226 29241732-9 2018 Inhibiting mitophagy by PGAM5 knockdown accelerated CCCP-induced apoptosis. Carbonyl Cyanide m-Chlorophenyl Hydrazone 52-56 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 24-29 29241732-13 2018 In conclusion, we demonstrated that PGAM5 regulates PINK1-Parkin-mediated mitophagy, which can exert a neuroprotective effect against CCCP-induced apoptosis. Carbonyl Cyanide m-Chlorophenyl Hydrazone 134-138 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 36-41 30642635-4 2019 Treatment of human hepatocellular carcinoma cells with carbonyl cyanide m-chlorophenyl hydrazone (CCCP), which activates endogenous PGAM5, promoted dephosphorylation and nuclear accumulation of Lipin-1. Carbonyl Cyanide m-Chlorophenyl Hydrazone 55-96 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 132-137 30642635-4 2019 Treatment of human hepatocellular carcinoma cells with carbonyl cyanide m-chlorophenyl hydrazone (CCCP), which activates endogenous PGAM5, promoted dephosphorylation and nuclear accumulation of Lipin-1. Carbonyl Cyanide m-Chlorophenyl Hydrazone 98-102 PGAM family member 5, mitochondrial serine/threonine protein phosphatase Homo sapiens 132-137