PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22537858-15 2012 IL-2 and IL-17 production by lymph node and spleen cells was higher in CIA animals than in PBS controls, but was not affected by statin administration. Lead 91-94 interleukin 2 Mus musculus 0-4 16289177-5 2006 At higher dietary Pb levels (40 and 400 ppm), a significant increase in IL-4 production was associated with a profound decrease in INF-gamma and IL-2 production. Lead 18-20 interleukin 2 Mus musculus 145-149 17633820-7 2007 In comparison with PBS control, the level of IL-2, IFN-gamma and TNF-alpha was (30.0+/-0) pg/ml, (65.0+/-0) pg/ml and (425.0+/-10.7) pg/ml respectively in the intramuscular group with a significant increase, but that of IL-4 decreased, with a value of (10.0+/-0) pg/ml. Lead 19-22 interleukin 2 Mus musculus 45-49 15885731-5 2005 Our data suggest that this increased proliferation is not coupled with increased IL-2 levels in the media as these were actually decreased with Pb treatment and that Pb-induced enhancement in the allo-proliferative response is only partially dependent upon IL-2. Lead 166-168 interleukin 2 Mus musculus 257-261 3263342-10 1988 The Pb-induced response being the least dependent on IL-2 lends support to the hypothesis that Pb, Ni and Zn may activate T-cells and/or B-cells by different mechanisms. Lead 4-6 interleukin 2 Mus musculus 53-57 1995485-5 1991 Four injections at weekly intervals of IL-2 in agar had as much local and systemic (against uninjected contralateral tumor implants in treated mice) therapeutic effect as the same total amount of IL-2 in PBS given in 20 daily injections over 4 weeks. Lead 204-207 interleukin 2 Mus musculus 196-200 3263342-10 1988 The Pb-induced response being the least dependent on IL-2 lends support to the hypothesis that Pb, Ni and Zn may activate T-cells and/or B-cells by different mechanisms. Lead 95-97 interleukin 2 Mus musculus 53-57 27134645-13 2016 Furthermore, a comparison with the PBS treatment group revealed significant decreases in the concentrations of several inflammatory cytokines, including IL-21, IL-10 and IL-17A (P < 0.05), as well as significant increases in the concentrations of IL-2 and IL-12P70 in the LZ-SMS treated SLE mice (P < 0.05). Lead 35-38 interleukin 2 Mus musculus 153-157