PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32014499-5	2020	Ang II increased the levels of AT1R, ROS, and NADPH oxidase (NOX), and the upregulations were mitigated by the AT1R blocker or NOX inhibitor.	NADP	46-51	angiotensin II receptor type 1	Homo sapiens	111-115	
25505418-8	2014	This Ang II-AT1R-NADPH-ROS signal triggers the opening of mitochondrial KATP channels and mitochondrial ROS production in a positive feedback loop.	NADP	17-22	angiotensin II receptor type 1	Homo sapiens	12-16	
23717285-2	2013	Several studies have revealed that increased reactive oxygen species (ROS) generated by nicotinamide adenine dinucleotide phosphate [NAD(P)H] oxidase, following activation of type 1 receptor (AT1R) by Angiotensin-(Ang) II, the main peptide of the Renin-Angiotensin-Aldosterone System (RAAS), is the central mechanism involved in Ang-II-derived hypertension.	NADP	88-131	angiotensin II receptor type 1	Homo sapiens	192-196	
18287671-4	2007	This association is mediated at least partially through interaction of angiotensin II (Ang II) with its receptor angiotensin receptor 1 (AT1R) in cardiovascular tissue, and subsequent activation of the nicotinamide adenine dinucleotide phosphate (NADPH) enzymatic complex, which finally leads to increased ROS production.	NADP	202-245	angiotensin II receptor type 1	Homo sapiens	137-141	
18287671-4	2007	This association is mediated at least partially through interaction of angiotensin II (Ang II) with its receptor angiotensin receptor 1 (AT1R) in cardiovascular tissue, and subsequent activation of the nicotinamide adenine dinucleotide phosphate (NADPH) enzymatic complex, which finally leads to increased ROS production.	NADP	247-252	angiotensin II receptor type 1	Homo sapiens	137-141