PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20124700-2	2010	The Y224D mutation of AKR1C21 reduced the K(m) value for NADP(H) by up to 80-fold and completely reversed the 17alpha stereospecificity of the enzyme.	NADP	57-64	aldo-keto reductase family 1, member C21	Mus musculus	22-29	
19237748-2	2009	In this paper, the crystal structure of a double mutant (G225P/G226P) of AKR1C21 in complex with the coenzyme NADP(+) and the inhibitor hexoestrol refined at 2.1 A resolution is presented.	NADP	110-114	aldo-keto reductase family 1, member C21	Mus musculus	73-80	
17909281-2	2007	The structure of the AKR1C21-NADPH binary complex was determined from an orthorhombic crystal belonging to space group P2(1)2(1)2(1) at a resolution of 1.8 A.	NADP	29-34	aldo-keto reductase family 1, member C21	Mus musculus	21-28	
17034817-0	2006	Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.	NADP	87-94	aldo-keto reductase family 1, member C21	Mus musculus	28-64