PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12005031-3 2001 Using NAD or NADP as the cofactor, 17beta-hydroxysteroid dehydrogenase (substrate: 5-androstene-3beta,17beta-diol) peaks were observed on pnd 16 for fetal Leydig cells and on pnd 19 and 37 for adult Leydig cells. NADP 13-17 aldo-keto reductase family 1, member C12 Rattus norvegicus 35-70 12005031-7 2001 To conclude: (1) Generally, a stronger reaction for 17beta-hydroxysteroid dehydrogenase is shown with NAD as cofactor than with NADP; using NADP, fetal Leydig cells show a stronger staining than adult Leydig cells. NADP 128-132 aldo-keto reductase family 1, member C12 Rattus norvegicus 52-87 16788056-6 2006 The coenzyme specificity, broad substrate specificity and inhibitor sensitivity of the enzyme differed from those of rat NADPH-dependent 17beta-hydroxysteroid dehydrogenase type 5, which was cloned from the liver and characterized using the recombinant enzyme. NADP 121-126 aldo-keto reductase family 1, member C12 Rattus norvegicus 137-172 9882448-6 1999 TBE-R1 utilized NADH or NADPH equally as cofactor, and the Km values of NADH and NADPH for TBE with TBE-R1 were estimated to be 15 and 29 microM, respectively. NADP 24-29 aldo-keto reductase family 1, member C12 Rattus norvegicus 0-6 9882448-6 1999 TBE-R1 utilized NADH or NADPH equally as cofactor, and the Km values of NADH and NADPH for TBE with TBE-R1 were estimated to be 15 and 29 microM, respectively. NADP 81-86 aldo-keto reductase family 1, member C12 Rattus norvegicus 100-106 6938086-6 1980 These findings may be explained by the observed decrease in 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) activity, due to an insufficient supply of NADPH, in the older vs. earlier stages of development. NADP 154-159 aldo-keto reductase family 1, member C12 Rattus norvegicus 60-96