PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12738234-7 2003 We conclude that (i) the upregulation of COX-2 protein expression after ischemic PC is mediated by a JAK1/2-STAT1/3-signaling cascade; (ii) COX-2 activity requires upregulated iNOS and iNOS-derived NO; and (iii) COX-2 forms complexes with iNOS, supporting a direct interaction between these two proteins. pc 81-83 Janus kinase 1 Mus musculus 101-115