PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25076060-4 2014 Benzyl- and benzyl methoxy-containing sulfide derivatives 4 and 5 were highly potent dual Mcl-1/Bim and Bcl-xL/Bim disruptors (IC50 values of 600 and 700 nM), whereas carboxylate-containing sulfide derivative 9 exhibited 16.4-fold more selectivity for disrupting Mcl-1/Bim over Bcl-xL/Bim binding. Sulfides 38-45 BCL2 like 1 Homo sapiens 104-110 25076060-4 2014 Benzyl- and benzyl methoxy-containing sulfide derivatives 4 and 5 were highly potent dual Mcl-1/Bim and Bcl-xL/Bim disruptors (IC50 values of 600 and 700 nM), whereas carboxylate-containing sulfide derivative 9 exhibited 16.4-fold more selectivity for disrupting Mcl-1/Bim over Bcl-xL/Bim binding. Sulfides 38-45 BCL2 like 1 Homo sapiens 278-284 20661185-8 2011 While expression of heme oxygenase 1 and cleaved caspase 3 did not differ, sulfide reduced the expression Bcl-xL and increased the activation of nuclear transcription factor kappaB. Sulfides 75-82 BCL2 like 1 Homo sapiens 106-112