PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11408266-6	2001	Our results with human-derived colonic epithelial NCM460 cells as a model system showed thiamine uptake to be 1) temperature- and energy dependent, 2) Na(+) independent, 3) increased with increasing buffer pH from 5 to 8 and after cell acidification but inhibited by amiloride, 4) saturable as a function of concentration, 5) inhibited by thiamine structural analogs but not by unrelated organic cations, and 6) inhibited by modulators of a Ca(2+)/calmodulin-mediated pathway.	Thiamine	88-96	calmodulin 1	Homo sapiens	448-458	
11408266-8	2001	These results demonstrate for the first time that human NCM460 colonocytes possess a specific carrier-mediated system for thiamine uptake that appears to be under the regulation of an intracellular Ca(2+)/calmodulin-mediated pathway.	Thiamine	122-130	calmodulin 1	Homo sapiens	205-215	
16705148-7	2006	Uptake of thiamin by HEK-293 cells also appeared to be under the regulation of an intracellular Ca(2+)/calmodulin-mediated pathway.	Thiamine	10-17	calmodulin 1	Homo sapiens	103-113	
16705148-9	2006	In addition, the uptake process appears to be under the regulation of an intracellular Ca(2+)/CaM-mediated pathway and also adaptively upregulated in thiamin deficiency via transcriptional regulatory mechanism(s) that involves both the hTHTR-1 and hTHTR-2.	Thiamine	150-157	calmodulin 1	Homo sapiens	94-97