PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24637331-0	2014	THI1, a protein involved in the biosynthesis of thiamin in Arabidopsis thaliana: structural analysis of THI1(A140V) mutant.	Thiamine	48-55	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	0-4	
26454882-9	2015	Total thiamin leaf content in THI1 plants was up approximately 2-fold compared with the wild type.	Thiamine	6-13	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	30-34	
26454882-11	2015	Resulting THI1 x THIC plants accumulated up to 3.4- and 2.6-fold more total thiamin than wild-type plants in leaf and seeds, respectively.	Thiamine	76-83	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	10-14	
24637331-0	2014	THI1, a protein involved in the biosynthesis of thiamin in Arabidopsis thaliana: structural analysis of THI1(A140V) mutant.	Thiamine	48-55	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	104-108	
24637331-3	2014	Here, we investigated THI1 and its mutant THI1(A140V), responsible for the thiamin auxotrophy in a A. thaliana mutant line, aiming to clarify the impact of this mutation in the stability and activity of THI1.	Thiamine	75-82	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	22-26	
24637331-3	2014	Here, we investigated THI1 and its mutant THI1(A140V), responsible for the thiamin auxotrophy in a A. thaliana mutant line, aiming to clarify the impact of this mutation in the stability and activity of THI1.	Thiamine	75-82	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	42-46	
24637331-3	2014	Here, we investigated THI1 and its mutant THI1(A140V), responsible for the thiamin auxotrophy in a A. thaliana mutant line, aiming to clarify the impact of this mutation in the stability and activity of THI1.	Thiamine	75-82	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	42-46	
24637331-4	2014	Recently, the THI1 orthologue (THI4) was revealed to be responsible for the donation of the sulfur atom from a cysteine residue to the thiazole ring in the thiamine intermediate.	Thiamine	156-164	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	14-18	
24637331-4	2014	Recently, the THI1 orthologue (THI4) was revealed to be responsible for the donation of the sulfur atom from a cysteine residue to the thiazole ring in the thiamine intermediate.	Thiamine	156-164	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	31-35	
24637331-9	2014	Hence, despite keeping its function in the early steps during the synthesis of TPP precursor, our studies have shown a decrease in the THI1(A140V) stability, which might be slowing down the biological activity of the mutant, and thus contributing to thiamin auxotrophy.	Thiamine	250-257	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	135-139	
12941878-1	2003	A point mutation in the thi1 gene, involved in the synthesis of thiamin, has been identified in a tz-201 mutant line of Arabidopsis thaliana.	Thiamine	64-71	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	24-28	
15897230-1	2005	The Arabidopsis thaliana THI1 protein is involved in thiamine biosynthesis and is targeted to both chloroplasts and mitochondria by N-terminal control regions.	Thiamine	53-61	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	25-29	
11575719-1	2001	thi1 has been recently isolated from Arabidopsis thaliana and is probably involved in both thiamine biosynthesis and as protection of organellar DNA from damage.	Thiamine	91-99	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	0-4	
11575719-2	2001	Studies of thiamine biosynthesis in plants suggests a plastid location for the pathway, which is in agreement with the predicted THI1 N-terminal chloroplastic transit peptide (TP).	Thiamine	11-19	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	129-133	
9367751-2	1997	The plant homolog thi1, from Arabidopsis thaliana, is also involved in thiamine biosynthesis; but was originally cloned due to its capacity to complement DNA repair deficient phenotypes in Escherichia coli.	Thiamine	71-79	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	18-22	
8790291-0	1996	Thi1, a thiamine biosynthetic gene in Arabidopsis thaliana, complements bacterial defects in DNA repair.	Thiamine	8-16	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	0-4	
8790291-9	1996	Thus, the cloned gene, named thi1, is likely to function in the biosynthesis of thiamine in plants.	Thiamine	80-88	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	29-33	
32441748-1	2020	Like fungi and some prokaryotes, plants use a thiazole synthase (THI4) to make the thiazole precursor of thiamin.	Thiamine	105-112	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	65-69