PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9537830-6 1998 The half-life of TNF-alpha induced membrane-associated ICAM-1 on rat astrocytes is approximately 5 h. The proteolytic cleavage process for the conversion of membrane-associated ICAM-1 to sICAM-1 was sensitive to Batimastat (BB94) and phosphoramidon, two inhibitors of metalloproteases, whereas inhibitors of serine-, cysteine-, aspartic-, and chymotrypsin-like proteases had no effect on this process. phosphoramidon 234-248 tumor necrosis factor Rattus norvegicus 17-26