PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31581004-2 2019 Among these derivatives, the chiral sulfoxide derivative (-)-4i exhibited excellent inhibition of EGFR kinase activity and L858R/T790M double mutant cell proliferation, with IC50 values of 4.10 nM and 10 nM, respectively. Sulfoxides 36-45 epidermal growth factor receptor Homo sapiens 98-102