PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22331418-3	2012	Ryanodine receptor (RyR) antagonists (ryanodine and tetracaine) inhibited both sparks and waves but increased global Ca(2+) and myogenic tone.	Tetracaine	52-62	ryanodine receptor 1, skeletal muscle	Mus musculus	0-18	
30181262-7	2018	Inhibition of RyRs with tetracaine and blocking of BK channels with paxilline restored myogenic tone to control levels, demonstrating that enhanced RyR and BK channel activity is responsible for the diminished pressure-induced constriction of arteries and arterioles from mdx mice.	Tetracaine	24-34	ryanodine receptor 1, skeletal muscle	Mus musculus	14-17	
29150444-6	2018	Preventing the SR leak with ryanodine receptor (RyR) blocker tetracaine restored SR load and increased myocyte contraction.	Tetracaine	61-71	ryanodine receptor 1, skeletal muscle	Mus musculus	28-46	
29150444-6	2018	Preventing the SR leak with ryanodine receptor (RyR) blocker tetracaine restored SR load and increased myocyte contraction.	Tetracaine	61-71	ryanodine receptor 1, skeletal muscle	Mus musculus	48-51	
22331418-3	2012	Ryanodine receptor (RyR) antagonists (ryanodine and tetracaine) inhibited both sparks and waves but increased global Ca(2+) and myogenic tone.	Tetracaine	52-62	ryanodine receptor 1, skeletal muscle	Mus musculus	20-23	
23381902-7	2013	This was verified by Ca(2+) spark analysis and pharmacological separation between RyR and InsP3R-dependent sarcoplasmic reticulum (SR)-Ca(2+) release (2-aminoethoxydiphenyl borate, xestospongin C, tetracaine).	Tetracaine	197-207	ryanodine receptor 1, skeletal muscle	Mus musculus	82-85	
18942758-10	2009	2-Aminoethoxydiphenyl borate, an inositol-1,4,5-trisphosphate (IP(3)) receptor antagonist, and the ryanodine receptor (RyR) antagonists tetracaine and ryanodine, inhibited the UTP-induced calcium transients.	Tetracaine	136-146	ryanodine receptor 1, skeletal muscle	Mus musculus	119-122	
19465516-6	2009	By contrast, a second RyR antagonist, tetracaine, relaxed agonist-contracted airways and inhibited agonist-induced Ca(2+) oscillations in a concentration-dependent manner.	Tetracaine	38-48	ryanodine receptor 1, skeletal muscle	Mus musculus	22-25