PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16505149-7	2006	The simulations show that (a) the properties of sparks in tetracaine are those expected if tetracaine reduces the number of active RyR Ca(2+) channels per spark, and (b) the single-channel Ca(2+) current of an RyR channel is <or=1.2 pA under physiological conditions.	Tetracaine	58-68	ryanodine receptor 2	Homo sapiens	131-134	
31710081-7	2019	The RyR antagonist tetracaine or RyR2 gene knockout (KO) suppresses hypoxia-induced responses as well.	Tetracaine	19-29	ryanodine receptor 2	Homo sapiens	4-7	
20056922-9	2010	Tetracaine experiments confirmed that SR Ca(2+) leak through RyR2 leads to the elevated diastolic Ca(2+) level.	Tetracaine	0-10	ryanodine receptor 2	Homo sapiens	61-65	
16505149-7	2006	The simulations show that (a) the properties of sparks in tetracaine are those expected if tetracaine reduces the number of active RyR Ca(2+) channels per spark, and (b) the single-channel Ca(2+) current of an RyR channel is <or=1.2 pA under physiological conditions.	Tetracaine	58-68	ryanodine receptor 2	Homo sapiens	210-213	
16505149-7	2006	The simulations show that (a) the properties of sparks in tetracaine are those expected if tetracaine reduces the number of active RyR Ca(2+) channels per spark, and (b) the single-channel Ca(2+) current of an RyR channel is <or=1.2 pA under physiological conditions.	Tetracaine	91-101	ryanodine receptor 2	Homo sapiens	131-134	
16505149-7	2006	The simulations show that (a) the properties of sparks in tetracaine are those expected if tetracaine reduces the number of active RyR Ca(2+) channels per spark, and (b) the single-channel Ca(2+) current of an RyR channel is <or=1.2 pA under physiological conditions.	Tetracaine	91-101	ryanodine receptor 2	Homo sapiens	210-213	
11973361-14	2002	RyR inhibition (by tetracaine) reduced only STOCs but not the InsP(3) transient.	Tetracaine	19-29	ryanodine receptor 2	Homo sapiens	0-3	
14634821-4	2004	Ryanodine (50 micro M), dantrolene (20 micro M) and tetracaine (50 micro M), putative antagonists of the RyR, attenuated the amperometric response significantly, decreasing the number and frequency of events as well as their amplitude.	Tetracaine	52-62	ryanodine receptor 2	Homo sapiens	105-108	
11600671-6	2001	The waves were blocked by the ryanodine receptor (RyR)-specific agents ryanodine and tetracaine, and potentiated by caffeine.	Tetracaine	85-95	ryanodine receptor 2	Homo sapiens	30-48	
11600671-6	2001	The waves were blocked by the ryanodine receptor (RyR)-specific agents ryanodine and tetracaine, and potentiated by caffeine.	Tetracaine	85-95	ryanodine receptor 2	Homo sapiens	50-53	
11306668-13	2001	Ouabain (500 nM) restored the steady-state charge movement that was previously abolished by the addition of 2.0 mM tetracaine in common with previous results of using ryanodine receptor (RyR)-specific agents.	Tetracaine	115-125	ryanodine receptor 2	Homo sapiens	167-185	
11306668-13	2001	Ouabain (500 nM) restored the steady-state charge movement that was previously abolished by the addition of 2.0 mM tetracaine in common with previous results of using ryanodine receptor (RyR)-specific agents.	Tetracaine	115-125	ryanodine receptor 2	Homo sapiens	187-190