PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29742927-5 2018 Furthermore, the pro-apoptotic signalling pathway induced by tetracaine was explored through detecting the activation of various caspases, the changes of mitochondrial transmembrane potential (MTP), the expression level of Bcl-2 family proteins and the amount of mitochondria-released apoptosis regulating proteins in cytoplasm. Tetracaine 61-71 caspase 8 Homo sapiens 129-137 29742927-8 2018 Tetracaine not only resulted in caspase-3, caspase-8 and caspase-9 activation and disruption of MTP but also downregulated Bcl-2 and Bcl-xL and upregulated Bad and Bax, along with the upregulation of cytoplasmic cytochrome c (Cyt. Tetracaine 0-10 caspase 8 Homo sapiens 43-52