PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11921051-10	2002	We show that flupirtine aborts etoposide-induced apoptosis in CLN1-, CLN2-, CLN3-, and CLN6-deficient as well as normal lymphoblasts.	flupirtine	13-23	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	76-80	
11921051-0	2002	Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons.	flupirtine	0-10	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	84-88	
11921051-11	2002	Flupirtine also prevents the death of CLN3- and CLN2-deficient postmitotic hNT neurons at the mitochondrial level.	flupirtine	0-10	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	38-42	
21556831-0	2011	Parent-reported benefits of flupirtine in juvenile neuronal ceroid lipofuscinosis (Batten disease; CLN3) are not supported by quantitative data.	flupirtine	28-38	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	42-81	
32796515-4	2020	Flupirtine and its new allyl carbamate derivative (compound 6) confer neuroprotective effects in CLN3-deficient cells.	flupirtine	0-10	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	97-101	
21556831-3	2011	Flupirtine has been shown in vitro to reduce apoptosis in CLN3 lymphocytes.	flupirtine	0-10	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	58-62	
21556831-4	2011	Based on that preclinical study, several children with JNCL were given flupirtine by their parents.	flupirtine	71-81	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	55-59	
21556831-6	2011	We administered a survey to parents of JNCL children to qualitatively assess flupirtine efficacy.	flupirtine	77-87	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	39-43	
21556831-9	2011	Twenty-one percent of survey responders reported administering flupirtine to their JNCL child, and 56% of these families perceived beneficial changes that they attributed to flupirtine.	flupirtine	63-73	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	83-87