PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33791156-7 2021 Through an initiate pilot screening with around 100 compounds, Flupirtine, a selective neuronal potassium channel opener, was identified as a potential TMPRSS2 inhibitor from an FDA-approved drug library by using this screening platform, and showed inhibitory effect on the TMPRSS-dependent infection of SARS-CoV-2 Spike-pseudotyped lentiviral particles. flupirtine 63-73 transmembrane serine protease 2 Homo sapiens 152-159 33791156-8 2021 This study describes a platform proven effective for rapidly screening of TMPRSS2 inhibitors, and suggests that Flupirtine may be worthy of further consideration of repurposing to treat COVID-19 patients. flupirtine 112-122 transmembrane serine protease 2 Homo sapiens 74-81