PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17345270-1 1985 Treatment of 28-hydroxyolean-12-enes with N-bromosuccinimide (NBS) in acetonitrile at room temperature afforded 12 alpha-bromooleanan-13beta, 28-epoxides in high yield. Bromosuccinimide 42-60 nibrin Homo sapiens 62-65 2557451-5 1989 N-bromoacetamide (NBA) and N-bromosuccinimide (NBS), reagents which remove inactivation gating in physiological preparations, transiently stimulate the sodium permeability of inside-out facing channels to high levels. Bromosuccinimide 27-45 nibrin Homo sapiens 47-50 3536898-0 1986 Identification of the tryptophan residue located at the low-affinity saccharide binding site of ricin D. The saccharide binding ability of the low affinity (LA-) binding site of ricin D was abrogated by N-bromosuccinimide (NBS)-oxidation, while in the presence of lactose the number of tryptophan residues eventually oxidized decreased by 1 mol/mol and the saccharide binding ability was retained (Hatakeyama et al., (1986) J. Biochem. Bromosuccinimide 203-221 nibrin Homo sapiens 223-226 482329-7 1979 In all cases the results of the analysis of the drugs studied either in the pure state or in their dosage forms comply with those given by N-bromo succinimide (NBS) and by the official methods, however this application is distinguished by simplicity and accuracy. Bromosuccinimide 139-158 nibrin Homo sapiens 160-163 557987-4 1977 N-Bromosuccinimide (NBS) inactivates galactose oxidase as two tryptophans are oxidized (Kosman, D. J., Ettinger, M. J., Bereman, R. D., and Giordano, R. S. (1977), Biochemistry, 16). Bromosuccinimide 0-18 nibrin Homo sapiens 20-23 192267-3 1977 We now show that N-bromosuccinimide (NBS) reduces enzymatic activity to 2% as two tryptophans are oxidized; only four residues are easily oxidized in the holoenzyme. Bromosuccinimide 17-35 nibrin Homo sapiens 37-40 20674-1 1976 A relationship between in vitro rate of oxidation by N-bromosuccinimide (NBS) and the pharmacologic activity (pA2) of different beta-adrenergic blockers for different blocking agent-tissue combinations has been studied. Bromosuccinimide 53-71 nibrin Homo sapiens 73-76 31408075-2 2019 NBS (bromo succinimide) was found to promote the thiocarbamation in good yields. Bromosuccinimide 5-22 nibrin Homo sapiens 0-3 31441965-1 2019 The covalent nature of strong N-Br N halogen bonds in a cocrystal (2) of N-bromosuccinimide (NBS) with 3,5-dimethylpyridine (lut) was determined from X-ray charge density studies and compared to a weak N-Br O halogen bond in pure crystalline NBS (1) and a covalent bond in bis(3-methylpyridine)bromonium cation (in its perchlorate salt (3). Bromosuccinimide 75-93 nibrin Homo sapiens 95-98 31441965-1 2019 The covalent nature of strong N-Br N halogen bonds in a cocrystal (2) of N-bromosuccinimide (NBS) with 3,5-dimethylpyridine (lut) was determined from X-ray charge density studies and compared to a weak N-Br O halogen bond in pure crystalline NBS (1) and a covalent bond in bis(3-methylpyridine)bromonium cation (in its perchlorate salt (3). Bromosuccinimide 75-93 nibrin Homo sapiens 246-249 28084743-1 2017 A protocol based on a newly developed N-bromosuccinimide (NBS)-induced cycloisomerization was described to prepare tricyclic azepino[4,5-b]indoles from simple beta-enaminoesters or beta-enaminones containing an indole unit. Bromosuccinimide 38-56 nibrin Homo sapiens 58-61 31334537-4 2019 MNPs have an excellent photoacoustic imaging (PAI) function and can be directly chelated with the magnetic resonance contrast agent Mn2+, and N-bromo succinimide (NBS) can be used as an oxidant to label the nanoparticles with the long half-life radionuclide 124I by an electrophilic substitution reaction. Bromosuccinimide 142-161 nibrin Homo sapiens 163-166 30859832-2 2019 The reaction of geranyl derivatives with N-bromosuccinimide (NBS) proceeds rapidly in CH2Cl2 to give the corresponding bromocyclization products in high yields as a ca. Bromosuccinimide 41-59 nibrin Homo sapiens 61-64 31396001-3 2019 This approach involving bromine as oxidant is superior to that using N-bromosuccimide (NBS) which produces byproduct succinimide often difficult to separate from the lactol products. Bromosuccinimide 69-85 nibrin Homo sapiens 87-90 29688727-5 2018 This technique is also effective with N-bromosuccinimide (NBS) as the brominating reagent. Bromosuccinimide 38-56 nibrin Homo sapiens 58-61 26944428-3 2016 Oil palm empty fruit bunch (OPEFB) fiber is a plant biomass that may be acetylated by acetic anhydride using N-bromosuccinimide (NBS) as a catalyst; here, the extent of acetylation may be calculated in terms of weight percent gain (WPG). Bromosuccinimide 109-127 nibrin Homo sapiens 129-132 26800214-2 2016 This oxo-amination process employs readily available N-bromosuccinimide (NBS) and secondary amines as N-sources and dimethyl sulfoxide (DMSO) as the oxidant and also leads to the production of amino alcohols in a single step on reduction, thus broadening the scope of this operationally simple reaction. Bromosuccinimide 53-71 nibrin Homo sapiens 73-76 26514681-3 2015 Here we utilize N-bromosuccinimide (NBS) and carry out oxidative bromination on platinum(II) drugs, namely cisplatin, carboplatin, and oxaliplatin, to obtain asymmetric and mono-bromo platinum(IV) prodrugs. Bromosuccinimide 16-34 nibrin Homo sapiens 36-39 26659026-1 2016 An N-Bromosuccinimide (NBS) promoted one pot strategy for the synthesis of alpha-amino functionalized aryl ketones starting from commercially available styrenes has been developed. Bromosuccinimide 3-21 nibrin Homo sapiens 23-26 25042109-1 2014 Two series of indolyldiketopiperazines were synthesized starting from methyl 1-substituted-1,2,3,4-tetrahydro-beta-carboline-3-carboxylate hydrochlorides via N-bromo-succinimide (NBS) as an important reagent. Bromosuccinimide 158-177 nibrin Homo sapiens 179-182 25699577-1 2015 A highly enantioselective bromocyclization of allylic amides with N-bromosuccinimide (NBS) was developed with DTBM-BINAP as a catalyst, affording chiral oxazolines with a tetrasubstituted carbon center in high yield with up to 99% ee. Bromosuccinimide 66-84 nibrin Homo sapiens 86-89 23816126-1 2013 A post-chemiluminescence (PCL) phenomenon was observed when palmatine was injected in a mixture of N-bromosuccinimide (NBS) and alkaline dichlorofluorescein (DCF) after the chemiluminescence (CL) reaction of NBS-alkaline DCF had finished. Bromosuccinimide 99-117 nibrin Homo sapiens 119-122 23175271-1 2013 A rapid and sensitive flow-injection chemiluminescence (FI-CL) method is described for the determination of diazepam based on its reaction with N-bromosuccinimide (NBS) in alkaline medium in the presence of dichlorofluorescein (DCF) as an effective energy-transfer agent. Bromosuccinimide 144-162 nibrin Homo sapiens 164-167 24102289-1 2013 Allylic amination reactions of alkenes, with an NBP (N-bromophthalimide) or NBS (N-bromosuccinimide)/DBU combination, were developed, in which both internal and external nitrogen nucleophiles can be installed directly. Bromosuccinimide 81-99 nibrin Homo sapiens 76-79 24261546-1 2014 A continuous-flow protocol for the bromination of benzylic compounds with N-bromosuccinimide (NBS) is presented. Bromosuccinimide 74-92 nibrin Homo sapiens 94-97 16526442-1 2005 A simple, sensitive, and selective method for determination of acetaminophen based on its oxidation using N-bromosuccinimide (NBS) to produce a highly fluorescent product. Bromosuccinimide 106-124 nibrin Homo sapiens 126-129 22516679-4 2012 All of the four impurities were produced as the by-products of the bromination reaction by NBS (N-bromosuccinimide) in the synthesis of Ib. Bromosuccinimide 96-114 nibrin Homo sapiens 91-94 21322580-6 2011 NMR, UV-vis, electron paramagnetic resonance (EPR), and single crystal X-ray diffraction analyses have shown that chemical oxidation of 1 with N-Bromosuccinimide (NBS) follows a complex process that gives multiple products, including the monomeric trivalent species kappa(P),kappa(C),kappa(N)-{2,6-(i-Pr(2)PO)(C(6)H(3))(CH NBn)}NiBr(2) (2). Bromosuccinimide 143-161 nibrin Homo sapiens 163-166 21322580-6 2011 NMR, UV-vis, electron paramagnetic resonance (EPR), and single crystal X-ray diffraction analyses have shown that chemical oxidation of 1 with N-Bromosuccinimide (NBS) follows a complex process that gives multiple products, including the monomeric trivalent species kappa(P),kappa(C),kappa(N)-{2,6-(i-Pr(2)PO)(C(6)H(3))(CH NBn)}NiBr(2) (2). Bromosuccinimide 143-161 nibrin Homo sapiens 323-326 20329791-2 2010 Moreover, upon treating the products from the reactions of methylenecyclobutanes with N-bromosuccinimide (NBS) through silica gel column chromatography, the corresponding substituted methylenecyclobutanols were obtained in moderate to good yields. Bromosuccinimide 86-104 nibrin Homo sapiens 106-109 18989812-6 2008 Our central idea was to inhibit the PLA(2) and Mel activities through histidine alkylation and or tryptophan oxidation (with pbb, para-bromo-phenacyl bromide, and/or NBS- N-bromosuccinimide, respectively) to make their encapsulations possible within stabilized liposomes. Bromosuccinimide 171-189 nibrin Homo sapiens 166-169 17386480-2 2007 Strong CL signal was generated during the reaction of nitrofurazone with H(2)O(2) and N-bromosuccinimide (NBS) in alkaline condition. Bromosuccinimide 86-104 nibrin Homo sapiens 106-109 15924325-2 2005 The method is based on the chemiluminescence (CL) generated during the oxidation of luminol by N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS) in alkaline medium. Bromosuccinimide 95-113 nibrin Homo sapiens 115-118 15837498-2 2005 ethanolamine, diethanolamine, and triethanolamine, by N-bromosuccinimide (NBS) in alkaline medium has been investigated in the absence as well as in the presence of cetyltrimethylammonium bromide (CTAB), a cationic surfactant. Bromosuccinimide 54-72 nibrin Homo sapiens 74-77 15366423-2 2004 Modification of colicin tryptophan residues by N-bromosuccinimide (NBS), as judged by the loss of tryptophan fluorescence, resulted in complete suppression of wild-type P178 channel activity in BLMs formed from fully saturated (diphytanoyl) phospholipids, both at the macroscopic-current and single-channel levels. Bromosuccinimide 47-65 nibrin Homo sapiens 67-70 15162206-1 2004 After the study of different phenylselanyl group activators, halogenation by N-bromosuccinimide (NBS) has been shown to be the most suitable manner for cyclizing beta-phenylselanyl amines into aziridines and also enabled production of oxazolidin-2-ones from N-Boc beta-phenylselanyl amines in excellent yield. Bromosuccinimide 77-95 nibrin Homo sapiens 97-100 7744774-5 1995 We have employed N-bromosuccinimide (NBS) to identify tryptophan as the exclusive aromatic donor in the energy transfer. Bromosuccinimide 17-35 nibrin Homo sapiens 37-40 12866071-5 2003 Traceless release of the coupling products from the solid support is achieved selectively under mild conditions and in high purity by oxidation of the aryl hydrazides to acyl diazenes with Cu(II) salts or N-bromosuccinimide (NBS) and subsequent nucleophilic attack of the acyl diazene intermediates. Bromosuccinimide 205-223 nibrin Homo sapiens 225-228 10811102-3 2000 Here we demonstrate that in the absence of DNA damage, a portion of p95 and MRE11 is concentrated in PML nuclear bodies (NBs); MRE11 localization to the NBs is p95-dependent. Bromosuccinimide 121-124 nibrin Homo sapiens 68-71 12659121-1 2002 N-Bromosuccinimide (NBS) was found to afford photochemical bromination of N-substituted 3-methyl-2-pyrazolin-5-one in chloroform solution. Bromosuccinimide 0-18 nibrin Homo sapiens 20-23 11814878-1 2002 N-Bromosuccinimide (NBS) is a known protein reagent able to modify amino acids and proteins, resulting in oxidation of tryptophan, tyrosine and histidine residues, as well as sulfhydryl, alcohol and phenol groups. Bromosuccinimide 0-18 nibrin Homo sapiens 20-23 9096953-5 1997 The reagents used for chemical modification were N-bromosuccinimide (NBS), chloramine T, and 2-hydroxy-5-nitrobenzyl bromide (HNBB), which abolished spasmoneme contractility at concentrations of 40-50 microM, 200-300 microM, and 4 mM, respectively. Bromosuccinimide 49-67 nibrin Homo sapiens 69-72 2265203-1 1990 N-Bromosuccinimide (NBS) completely inactivated xylanases from Chainia and alkalophilic and thermophilic (AT) Bacillus with a concomittant decrease in absorption at 280 nm and with second-order rate constants of 10,500 and 5000 M-1.min-1, respectively at pH 6.0 and 25 degrees C. The kinetic analysis of inactivation indicated that one and three tryptophan residues were essential for the xylanase activity from Chainia and Bacillus, respectively. Bromosuccinimide 0-18 nibrin Homo sapiens 20-23 18965976-2 1994 The spectrophotometric procedure depends upon the reaction of ketoprofen with N-bromosuccinimide (NBS). Bromosuccinimide 78-96 nibrin Homo sapiens 98-101 8390296-2 1993 The nature of the poly(P) and ATP sites was investigated by using N-bromosuccinimide (NBS) as a probe for the involvement of tryptophan in substrate binding and/or catalysis. Bromosuccinimide 66-84 nibrin Homo sapiens 86-89 2074534-1 1990 Twelve purines oxidized with 4,5-dimethyl-o-phenylenediamine (DMPD) was found to react with N-bromosuccinimide (NBS) to give fluorescent derivatives. Bromosuccinimide 92-110 nibrin Homo sapiens 112-115