PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18992797-3	2008	We investigated whether expression of human glutathione S-transferase P1 (hGSTP1) would differentially protect cells against the cytotoxicity or mutagenicity of 5MC or its 1,2-dihydrodiol intermediate (5MC-1,2-diol) in V79MZ cells with activation via stably transfected human CYP1B1 (hCYP1B1) as compared to activation by human CYP1A1 (hCYP1A1).	5mc-1,2-diol	202-214	glutathione S-transferase pi 1	Homo sapiens	44-72	
18992797-5	2008	Cells co-expressing either hCYP1B1 or hCYP1A1 together with hGSTP1 were 2-fold less sensitive to 5MC or 5MC-1,2-diol cytotoxicity than their CYP-only parent lines.	5mc-1,2-diol	104-116	glutathione S-transferase pi 1	Homo sapiens	60-66	
18992797-7	2008	Coexpression of hGSTP1 with either hCYP reduced 5MC or 5MC-1,2-diol mutagenicity by 1.4-4.5-fold compared to the corresponding hCYP-only expressing cell lines.	5mc-1,2-diol	55-67	glutathione S-transferase pi 1	Homo sapiens	16-22	
18992797-10	2008	These studies show that the relative efficacy of protection by hGSTP1 against mutagenicity of 5MC or 5MC-1,2-diol is in part determined by the specific CYP pathway that catalyzes activation to the toxic or mutagenic metabolites.	5mc-1,2-diol	101-113	glutathione S-transferase pi 1	Homo sapiens	63-69