PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19062296-4 2009 Several different scaffolds capable of inhibiting carboxylesterases have been reported, including organophosphates, carbamates, trifluoromethyl ketone-containing structures (TFKs), and aromatic ethane-1,2-diones. ethane-1,2-diones 194-211 carboxylesterase 1 Homo sapiens 50-67 17941623-4 2007 In this paper, we have further examined the inhibitory properties of ethane-1,2-diones toward these proteins and determined that, when the carbonyl oxygen atoms are cis-coplanar, the compounds demonstrate specificity for hCE1. ethane-1,2-diones 69-86 carboxylesterase 1 Homo sapiens 221-225