PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30326372-6	2018	The compounds 9h and 9k also decreased liposaccharide (LPS)-induced IL-6, IL-1beta and vascular cell adhesion molecule-1 (VCAM-1) mRNA expression, both in vitro and in an in vivo model of ALI.	lps	55-58	interleukin 1 beta	Mus musculus	74-82	
28104349-7	2017	In vitro study, the results showed that IA inhibited production of IL-1beta, IL-6 and TNF-alpha at transcriptional and translational levels in RAW 264.7 cells induced by LPS.	lps	170-173	interleukin 1 beta	Mus musculus	67-75	
28427134-16	2017	The mRNA expressions of TNF-alpha and IL-1beta of cells in LPS control group were 2.97+-0.17 and 3.07+-0.60, respectively, while those in BMX-IN-1+ LPS group were 2.31+-0.94 and 2.55+-0.73, respectively, with the 4 values significantly higher than those in blank control group (with P values below 0.01).	lps	59-62	interleukin 1 beta	Mus musculus	38-46	
28427134-16	2017	The mRNA expressions of TNF-alpha and IL-1beta of cells in LPS control group were 2.97+-0.17 and 3.07+-0.60, respectively, while those in BMX-IN-1+ LPS group were 2.31+-0.94 and 2.55+-0.73, respectively, with the 4 values significantly higher than those in blank control group (with P values below 0.01).	lps	148-151	interleukin 1 beta	Mus musculus	38-46	
28427134-17	2017	The mRNA expressions of TNF-alpha and IL-1beta of cells in BMX-IN-1+ LPS group were significantly lower than those in LPS control group (with P values below 0.05).	lps	69-72	interleukin 1 beta	Mus musculus	38-46	
28427134-17	2017	The mRNA expressions of TNF-alpha and IL-1beta of cells in BMX-IN-1+ LPS group were significantly lower than those in LPS control group (with P values below 0.05).	lps	118-121	interleukin 1 beta	Mus musculus	38-46	
28427134-21	2017	Conclusions: BMX can increase the production of pro-inflammatory cytokines TNF-alpha and IL-1beta from mouse mononuclear-macrophages induced by LPS, which may be associated with the activation of the p38MAPK pathway by BMX.	lps	144-147	interleukin 1 beta	Mus musculus	89-97	
19892005-5	2010	However, in the brains of LPS-exposed mice, ultrafine TiO(2) significantly elevated proinflammatory cytokine interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) mRNAs, and IL-1beta protein levels.	lps	26-29	interleukin 1 beta	Mus musculus	109-126	
26155222-4	2013	Lipopolysaccarides (LPS) induced the expression of TNF-alpha, IL-1beta, and IL-6.	lps	20-23	interleukin 1 beta	Mus musculus	62-70	
21147093-9	2011	LPS-induced phosphorylation of IkappaBalpha and p38 MAPK was blocked by Biochanin-A and it inhibited IL-6, IL-1beta and TNF-alpha production in RAW264.7 cells indicating its anti-inflammatory activity in association with anti-proliferation.	lps	0-3	interleukin 1 beta	Mus musculus	107-115	
24972244-8	2014	Mangiferin (10 muM) inhibited LPS-stimulated expression of TNF-alpha, IL-1beta and IL-6 by 81.0%, 89.5% and 88.3%, respectively, whereas it increased IL-10 expression by 131.8% compared to LPS-nontreated group.	lps	30-33	interleukin 1 beta	Mus musculus	70-78	
26155222-11	2013	Fenofibrate inhibited LPS-induced TNF-alpha, IL-1beta, and IL-6 production in the serum and liver.	lps	22-25	interleukin 1 beta	Mus musculus	45-53	
19892005-5	2010	However, in the brains of LPS-exposed mice, ultrafine TiO(2) significantly elevated proinflammatory cytokine interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) mRNAs, and IL-1beta protein levels.	lps	26-29	interleukin 1 beta	Mus musculus	128-136	
19892005-5	2010	However, in the brains of LPS-exposed mice, ultrafine TiO(2) significantly elevated proinflammatory cytokine interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) mRNAs, and IL-1beta protein levels.	lps	26-29	interleukin 1 beta	Mus musculus	193-201	
17965763-6	2007	MCE also reduced the concentration of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and interleukin-6 (IL-6) in the Raw264.7 cells that were activated by LPS.	lps	178-181	interleukin 1 beta	Mus musculus	79-96	
17675415-5	2007	Moreover, we documented that peripherally injected LPS triggers a specific spatiotemporal pattern of expression of IL-1beta mRNA within the brain, suggesting that IL-1beta could be a major regulator of the central inflammatory cascade.	lps	51-54	interleukin 1 beta	Mus musculus	115-123	
17675415-5	2007	Moreover, we documented that peripherally injected LPS triggers a specific spatiotemporal pattern of expression of IL-1beta mRNA within the brain, suggesting that IL-1beta could be a major regulator of the central inflammatory cascade.	lps	51-54	interleukin 1 beta	Mus musculus	163-171	
17965763-6	2007	MCE also reduced the concentration of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and interleukin-6 (IL-6) in the Raw264.7 cells that were activated by LPS.	lps	178-181	interleukin 1 beta	Mus musculus	98-106	
12918124-11	2003	While the liver HO-1 expression in TNF KO mice was much lower than that in C57 mice following the same LPS treatment, IL-1beta KO had a slight influence on liver HO-1 expression following LPS treatment.	lps	188-191	interleukin 1 beta	Mus musculus	118-126	
12918124-0	2003	TLR4 mediates LPS-induced HO-1 expression in mouse liver: role of TNF-alpha and IL-1beta.	lps	14-17	interleukin 1 beta	Mus musculus	80-88	
12918124-14	2003	LPS-induced HO-1 expression is mainly mediated by endogenous TNF-alpha, but only partially by endogenous IL-1beta.	lps	0-3	interleukin 1 beta	Mus musculus	105-113	
8920166-5	1996	Progesterone (10(-7) M) modestly (40%) reduced the levels of IL-6 mRNA and protein during culture, whereas LPS dramatically (8-fold) and rapidly induced IL-6 and IL-1 beta mRNAs and proteins.	lps	107-110	interleukin 1 beta	Mus musculus	162-171	
8920166-9	1996	After LPS injection, IL-1 beta immunopositive cells were dispersed in the myometrium and mesometrial deciduum.	lps	6-9	interleukin 1 beta	Mus musculus	21-30	
1727430-2	1992	After in vitro activation by lipopolysaccharide acid (LPS), these macrophages hyperexpress IL-1 beta mRNA and hyperproduce IL-1 protein in comparison with +/+ controls.	lps	54-57	interleukin 1 beta	Mus musculus	91-100	
1727430-4	1992	The hyperexpression of IL-1 beta mRNA in sg/sg macrophages is present whatever the duration of LPS stimulation, even for periods as short as 15 min, although it reaches a maximum after 4 h of stimulation.	lps	95-98	interleukin 1 beta	Mus musculus	23-32