PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11256945-7	2001	LPS induced endogenous IL-1beta biosynthesis in a time-dependent manner; the administration of exogenous recombinant human interleukin 1 (rhIL-1) resulted in a dose-dependent activation of NF-kappaB.	lps	0-3	interleukin 1 alpha	Homo sapiens	123-144	
8704096-1	1996	We evaluate the influence of IL-4, IL-10 and TGF-beta upon the release of IL-1 alpha, tumor necrosis factor-alpha (TNF-alpha), and IL-6 by lipopolisaccharide (LPS, 1 microgram/ml) stimulated alveolar macrophages (AM).	lps	159-162	interleukin 1 alpha	Homo sapiens	74-84	
8704096-2	1996	IL-4 reduced TNF-alpha release, in a dose dependent manner, to 62% and IL-1 alpha release to 42% of LPS-stimulated AM without IL-4.	lps	100-103	interleukin 1 alpha	Homo sapiens	71-81	
2509610-11	1989	PBMC cultured with LPS and latex beads in the absence of serum released 30-40K Mr IL-1 alpha, as well as 17K Mr IL-1 alpha and 17K Mr IL-1 beta.	lps	19-22	interleukin 1 alpha	Homo sapiens	82-92	
2477997-2	1989	Exposure to E. coli lipopolysacharide (LPS) resulted in a dose- and time-dependent increase of IL-1 activity in monocytes culture supernatants.	lps	39-42	interleukin 1 alpha	Homo sapiens	95-99	
2477997-3	1989	Maximal levels of secreted IL-1 in response to 10 ng LPS/ml were obtained at 18 h. PGE1, PGE2, cholera toxin (CT) and the phosphodiesterase inhibitor, isobutylmethylxanthin (IBMX), when added with LPS, resulted in a dose-dependent increase in cellular cAMP and in secreted IL-1.	lps	53-56	interleukin 1 alpha	Homo sapiens	27-31	
2477997-3	1989	Maximal levels of secreted IL-1 in response to 10 ng LPS/ml were obtained at 18 h. PGE1, PGE2, cholera toxin (CT) and the phosphodiesterase inhibitor, isobutylmethylxanthin (IBMX), when added with LPS, resulted in a dose-dependent increase in cellular cAMP and in secreted IL-1.	lps	197-200	interleukin 1 alpha	Homo sapiens	27-31	
2477997-4	1989	Maximal levels of secreted IL-1 were 2.5-5.0-fold over LPS alone.	lps	55-58	interleukin 1 alpha	Homo sapiens	27-31