PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24920677-4	2014	Here we report that flow shear stress raised [Ca(2+)]cyt in PASMC, while the shear stress-mediated rise in [Ca(2+)]cyt and the protein expression level of TRPM7 and TRPV4 channels were significantly greater in IPAH-PASMC than in normal PASMC.	pasmc	215-220	transient receptor potential cation channel subfamily V member 4	Homo sapiens	165-170	
25815455-9	2015	In human PASMC, inhibition of TRPV4 blocked the hypoxia-induced Ca influx and myosin light chain phosphorylation.	pasmc	9-14	transient receptor potential cation channel subfamily V member 4	Homo sapiens	30-35	
24920677-5	2014	Blockade of TRPM7 by 2-APB or TRPV4 by Ruthenium red inhibited shear stress-induced rise in [Ca(2+)]cyt in normal and IPAH-PASMC, while activation of TRPM7 by bradykinin or TRPV4 by 4alphaPDD induced greater increase in [Ca(2+)]cyt in IPAH-PASMC than in normal PASMC.	pasmc	123-128	transient receptor potential cation channel subfamily V member 4	Homo sapiens	30-35	
24920677-8	2014	In conclusion, upregulated mechanosensitive channels (e.g., TRPM7, TRPV4, TRPC6) contribute to the enhanced [Ca(2+)]cyt increase induced by shear stress in PASMC from IPAH patients.	pasmc	156-161	transient receptor potential cation channel subfamily V member 4	Homo sapiens	67-72