PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26702130-3 2016 Therefore, we first hypothesized that PICK1 facilitates ASIC1-dependent Ca(2+) influx in PASMC by promoting plasma membrane localization. pasmc 89-94 acid sensing ion channel subunit 1 Rattus norvegicus 56-61 26702130-1 2016 Acid-sensing ion channel 1 (ASIC1) contributes to Ca(2+) influx and contraction in pulmonary arterial smooth muscle cells (PASMC). pasmc 123-128 acid sensing ion channel subunit 1 Rattus norvegicus 0-26 26702130-1 2016 Acid-sensing ion channel 1 (ASIC1) contributes to Ca(2+) influx and contraction in pulmonary arterial smooth muscle cells (PASMC). pasmc 123-128 acid sensing ion channel subunit 1 Rattus norvegicus 28-33 26702130-6 2016 These data suggest PICK1 imparts a basal inhibitory effect on ASIC1 Ca(2+) entry in PASMC and led to an alternative hypothesis that PICK1 facilitates the interaction between ASIC1 and negative intracellular modulators, namely PKC and/or the calcium-calmodulin-activated phosphatase calcineurin. pasmc 84-89 acid sensing ion channel subunit 1 Rattus norvegicus 62-67 26702130-6 2016 These data suggest PICK1 imparts a basal inhibitory effect on ASIC1 Ca(2+) entry in PASMC and led to an alternative hypothesis that PICK1 facilitates the interaction between ASIC1 and negative intracellular modulators, namely PKC and/or the calcium-calmodulin-activated phosphatase calcineurin. pasmc 84-89 acid sensing ion channel subunit 1 Rattus norvegicus 174-179 24993130-8 2014 Whereas H2O2 inhibited ASIC1-dependent SOCE in PASMC from control and CH animals, addition of catalase augmented ASIC1-mediated SOCE in PASMC from control rats but had no further effect in PASMC from CH rats. pasmc 47-52 acid sensing ion channel subunit 1 Rattus norvegicus 23-28