PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15257984-3 2005 The mechanism by which overexpression of CGRP inhibits proliferation in pulmonary artery smooth muscle cells (PASMC) and ASMC following in vitro transfection by the gene coding for prepro-CGRP was investigated. pasmc 110-115 calcitonin related polypeptide alpha Homo sapiens 41-45 15257984-6 2005 In this study, CGRP was shown to inhibit ASMC and PASMC proliferation. pasmc 50-55 calcitonin related polypeptide alpha Homo sapiens 15-19 15257984-7 2005 In PASMC transfected with CGRP and exposed to a PKA inhibitor (PKAi), cell proliferation was restored. pasmc 3-8 calcitonin related polypeptide alpha Homo sapiens 26-30 15257984-9 2005 PASMC treated with CGRP and a PKG inhibitor (PKGi) recovered from inhibition of proliferation induced by CGRP. pasmc 0-5 calcitonin related polypeptide alpha Homo sapiens 19-23 15257984-9 2005 PASMC treated with CGRP and a PKG inhibitor (PKGi) recovered from inhibition of proliferation induced by CGRP. pasmc 0-5 calcitonin related polypeptide alpha Homo sapiens 105-109 15257984-12 2005 It is concluded that p53 plays a role in CGRP-induced inhibition of cell proliferation and cAMP/PKA appears to mediate this effect in ASMC and PASMC, whereas cGMP appears to be involved in PASMC proliferation. pasmc 143-148 calcitonin related polypeptide alpha Homo sapiens 41-45 15257984-12 2005 It is concluded that p53 plays a role in CGRP-induced inhibition of cell proliferation and cAMP/PKA appears to mediate this effect in ASMC and PASMC, whereas cGMP appears to be involved in PASMC proliferation. pasmc 189-194 calcitonin related polypeptide alpha Homo sapiens 41-45