PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18424621-10	2008	For both protein, as measured by Western blotting, and mRNA, expression of STIM1, TRPC1, TRPC6, and TRPC4 was greater in distal than proximal PASMC and PA.	pasmc	142-147	transient receptor potential cation channel subfamily C member 6	Homo sapiens	89-94	
26968768-5	2016	Downregulation of CaSR or TRPC6 with siRNA inhibited Ca(2+)-induced [Ca(2+)]cyt increase in IPAH-PASMC (in which CaSR is upregulated), whereas overexpression of CaSR or TRPC6 enhanced Ca(2+)-induced [Ca(2+)]cyt increase in normal PASMC (in which CaSR expression level is low).	pasmc	97-102	transient receptor potential cation channel subfamily C member 6	Homo sapiens	26-31	
15358862-4	2004	Normal human PASMC expressed multiple canonical TRP (TRPC) isoforms; TRPC6 was highly expressed and TRPC3 was minimally expressed.	pasmc	13-18	transient receptor potential cation channel subfamily C member 6	Homo sapiens	69-74	
15358862-5	2004	The protein expression of TRPC6 in normal PASMC closely correlated with the expression of Ki67, suggesting that TRPC6 expression is involved in the transition of PASMC from quiescent phase to mitosis.	pasmc	42-47	transient receptor potential cation channel subfamily C member 6	Homo sapiens	26-31	
15358862-5	2004	The protein expression of TRPC6 in normal PASMC closely correlated with the expression of Ki67, suggesting that TRPC6 expression is involved in the transition of PASMC from quiescent phase to mitosis.	pasmc	162-167	transient receptor potential cation channel subfamily C member 6	Homo sapiens	26-31	
15358862-5	2004	The protein expression of TRPC6 in normal PASMC closely correlated with the expression of Ki67, suggesting that TRPC6 expression is involved in the transition of PASMC from quiescent phase to mitosis.	pasmc	162-167	transient receptor potential cation channel subfamily C member 6	Homo sapiens	112-117	
12529250-3	2003	We tested the hypothesis that platelet-derived growth factor (PDGF)-mediated PASMC growth involves upregulation of c-Jun and TRPC6, a transient receptor potential cation channel.	pasmc	77-82	transient receptor potential cation channel subfamily C member 6	Homo sapiens	125-177	
12529250-7	2003	Downregulation of TRPC6 using an antisense oligonucleotide specifically for human TRPC6 decreased CCE and inhibited PDGF-mediated PASMC proliferation.	pasmc	130-135	transient receptor potential cation channel subfamily C member 6	Homo sapiens	18-23	
12529250-7	2003	Downregulation of TRPC6 using an antisense oligonucleotide specifically for human TRPC6 decreased CCE and inhibited PDGF-mediated PASMC proliferation.	pasmc	130-135	transient receptor potential cation channel subfamily C member 6	Homo sapiens	82-87	
12529250-8	2003	These results suggest that PDGF-mediated PASMC proliferation is associated with c-Jun/STAT3-induced upregulation of TRPC6 expression.	pasmc	41-46	transient receptor potential cation channel subfamily C member 6	Homo sapiens	116-121	
29351410-9	2018	The basal protein expression levels of STIM1/2, Orai1/2, and TRPC6 were higher in CASMC than in PASMC, but hypoxia (3% O2 for 72 h) significantly upregulated protein expression levels of STIM1/STIM2, Orai1/Orai2, and TRPC6 and increased the resting [Ca2+]cyt only in PASMC, but not in CASMC.	pasmc	96-101	transient receptor potential cation channel subfamily C member 6	Homo sapiens	61-66	
26968768-4	2016	Here, we report that CaSR functionally interacts with TRPC6 to regulate [Ca(2+)]cyt in PASMC.	pasmc	87-92	transient receptor potential cation channel subfamily C member 6	Homo sapiens	54-59	
24920677-8	2014	In conclusion, upregulated mechanosensitive channels (e.g., TRPM7, TRPV4, TRPC6) contribute to the enhanced [Ca(2+)]cyt increase induced by shear stress in PASMC from IPAH patients.	pasmc	156-161	transient receptor potential cation channel subfamily C member 6	Homo sapiens	74-79