PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23353150-8 2013 CONCLUSION: Activation of calcineurin/NFAT signaling pathway mediates ET-1-induced PASMC proliferation by stimulating PDE5 expression, which further degrades cGMP. pasmc 83-88 phosphodiesterase 5A Homo sapiens 118-122 19793106-18 2010 The results of the present study indicate that PDE5 inhibition suppresses RhoA/ROCK-mediated MMP-2 production by PASMC, which may contribute to the regulation of pulmonary vascular remodelling. pasmc 113-118 phosphodiesterase 5A Homo sapiens 47-51 16980375-4 2007 Real-time PCR and immunoblotting demonstrated that the expression of PDE1A, PDE1C, PDE3B, and PDE5A was enhanced in PASMC from both IPAH and SPH patients compared with control PASMC. pasmc 116-121 phosphodiesterase 5A Homo sapiens 94-99 16980375-4 2007 Real-time PCR and immunoblotting demonstrated that the expression of PDE1A, PDE1C, PDE3B, and PDE5A was enhanced in PASMC from both IPAH and SPH patients compared with control PASMC. pasmc 176-181 phosphodiesterase 5A Homo sapiens 94-99