PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24920677-5	2014	Blockade of TRPM7 by 2-APB or TRPV4 by Ruthenium red inhibited shear stress-induced rise in [Ca(2+)]cyt in normal and IPAH-PASMC, while activation of TRPM7 by bradykinin or TRPV4 by 4alphaPDD induced greater increase in [Ca(2+)]cyt in IPAH-PASMC than in normal PASMC.	pasmc	123-128	transient receptor potential cation channel subfamily M member 7	Homo sapiens	12-17	
24920677-4	2014	Here we report that flow shear stress raised [Ca(2+)]cyt in PASMC, while the shear stress-mediated rise in [Ca(2+)]cyt and the protein expression level of TRPM7 and TRPV4 channels were significantly greater in IPAH-PASMC than in normal PASMC.	pasmc	215-220	transient receptor potential cation channel subfamily M member 7	Homo sapiens	155-160	
24920677-6	2014	The bradykinin-mediated activation of TRPM7 also led to a greater increase in [Mg(2+)]cyt in IPAH-PASMC than in normal PASMC.	pasmc	98-103	transient receptor potential cation channel subfamily M member 7	Homo sapiens	38-43	
24920677-8	2014	In conclusion, upregulated mechanosensitive channels (e.g., TRPM7, TRPV4, TRPC6) contribute to the enhanced [Ca(2+)]cyt increase induced by shear stress in PASMC from IPAH patients.	pasmc	156-161	transient receptor potential cation channel subfamily M member 7	Homo sapiens	60-65