PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12529250-8	2003	These results suggest that PDGF-mediated PASMC proliferation is associated with c-Jun/STAT3-induced upregulation of TRPC6 expression.	pasmc	41-46	signal transducer and activator of transcription 3	Homo sapiens	86-91	
20522789-8	2010	IL-13, signaling via STAT3 and STAT6, suppressed proliferation of paSMC by promoting G(0)/G(1) arrest.	pasmc	66-71	signal transducer and activator of transcription 3	Homo sapiens	21-26	
23525442-6	2013	As RAGE is one of the most upregulated proteins in PAH patients" lungs and a strong STAT3 activator, we hypothesized that by activating STAT3, RAGE induces BMPR2 and PPARgamma downregulation, promoting PAH-PASMC proliferation and resistance to apoptosis.	pasmc	206-211	signal transducer and activator of transcription 3	Homo sapiens	136-141	
21951574-9	2011	Inhibition of the STAT3 pathway abrogates KLF5 activation in PAH-PASMC.	pasmc	65-70	signal transducer and activator of transcription 3	Homo sapiens	18-23	
15939634-10	2005	These findings suggest that hypoxia induces the expression of JAK1, JAK2, JAK3 and phospho-STAT1 and -STAT3 in PASMC.	pasmc	111-116	signal transducer and activator of transcription 3	Homo sapiens	102-107	
29339076-11	2018	In conclusion, it may suggest that the suppression of miR-361-5p suppressed PASMC survival and migration by targeting ABCA1 and inhibiting the JAK2/STAT3 pathway.	pasmc	76-81	signal transducer and activator of transcription 3	Homo sapiens	148-153	
29358461-6	2018	In summary, these data indicate that upregulated STIM2 in PAH-PASMCs, by raising the resting [Ca2+]cyt, contributes to enhancing PASMC proliferation by activating the CREB, STAT3, AKT, and NFAT signaling pathways and stimulating PASMC proliferation.	pasmc	62-67	signal transducer and activator of transcription 3	Homo sapiens	173-178	
30211651-7	2018	Moreover, we exhibited that miR-1181 targeting STAT3 formed a regulatory axis to modulate PASMC proliferation.	pasmc	90-95	signal transducer and activator of transcription 3	Homo sapiens	47-52	
28187784-16	2017	CONCLUSIONS: Collectively, this study suggests that MSCs modified with let-7a may ameliorate the progression of PAH by inhibiting PASMC growth through the STAT3-BMPR2 signaling, supporting a promising therapeutic strategy for PAH patients.	pasmc	130-135	signal transducer and activator of transcription 3	Homo sapiens	155-160