PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16729969-2	2006	Heparin which inhibits pulmonary artery smooth muscle cell (PASMC) proliferation increases the levels of two CDKIs, p21 and p27, although only p27 is important in inhibition of PASMC growth in vitro and in vivo.	pasmc	60-65	cyclin-dependent kinase inhibitor 1B	Mus musculus	143-146	
20558775-6	2011	This study demonstrates that the RhoA/ROCK pathway plays an important role in heparin inhibition on PASMC proliferation, and reveals that heparin inhibits PASMC proliferation through GEF-H1/RhoA/ROCK/p27 signaling pathway, by down-regulating GEF-H1, RhoA, and ROCK, and then up-regulating p27.	pasmc	155-160	cyclin-dependent kinase inhibitor 1B	Mus musculus	200-203	
20558775-6	2011	This study demonstrates that the RhoA/ROCK pathway plays an important role in heparin inhibition on PASMC proliferation, and reveals that heparin inhibits PASMC proliferation through GEF-H1/RhoA/ROCK/p27 signaling pathway, by down-regulating GEF-H1, RhoA, and ROCK, and then up-regulating p27.	pasmc	155-160	cyclin-dependent kinase inhibitor 1B	Mus musculus	289-292	
16729969-2	2006	Heparin which inhibits pulmonary artery smooth muscle cell (PASMC) proliferation increases the levels of two CDKIs, p21 and p27, although only p27 is important in inhibition of PASMC growth in vitro and in vivo.	pasmc	60-65	cyclin-dependent kinase inhibitor 1B	Mus musculus	124-127	
16729969-7	2006	This study provides an expression profile of cell cycle regulating genes under hypoxia in mice with hypoxia-induced pulmonary hypertension and strengthens the previous finding that p27 is the only CDKI involved in heparin regulation of PASMC proliferation and hypoxia-induced pulmonary hypertension.	pasmc	236-241	cyclin-dependent kinase inhibitor 1B	Mus musculus	181-184	
16195480-4	2005	In vitro, loss of the p27 gene negated the inhibitory effect of heparin on PASMC proliferation, but p21 was not critical for this inhibition.	pasmc	75-80	cyclin-dependent kinase inhibitor 1B	Mus musculus	22-25	
11713109-8	2001	PASMC obtained from p27(Kip1-/-) mice showed a 2-fold increase in [(3)H]thymidine incorporation (at 24 h) and cell proliferation compared with p27(Kip1+/+) PASMC when cultured in 10% fetal bovine serum (FBS).	pasmc	0-5	cyclin-dependent kinase inhibitor 1B	Mus musculus	20-23	
11713109-8	2001	PASMC obtained from p27(Kip1-/-) mice showed a 2-fold increase in [(3)H]thymidine incorporation (at 24 h) and cell proliferation compared with p27(Kip1+/+) PASMC when cultured in 10% fetal bovine serum (FBS).	pasmc	0-5	cyclin-dependent kinase inhibitor 1B	Mus musculus	24-28