PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35175493-7	2022	The obtained results illustrated that the differentiation medium supplemented with T-E2 increased not only the ALP enzyme activity and the content of calcium but also the osteogenic-related gene and protein expressions on the 14th day.	Estradiol	85-87	ATHS	Homo sapiens	111-114	
32339349-6	2020	In this research, the result of ALP activity assay, calcium content and Real-time RT-PCR assay and also all tests of differentiation staining have shown that 17-beta estradiol has been recognized as an enhancing factor of osteogenic differentiation.	Estradiol	158-175	ATHS	Homo sapiens	32-35	
10589811-8	1999	at Estradiol 20 ng/ml significantly enhanced the ALP activity and mineralized nodule formation compared to the control.	Estradiol	3-12	ATHS	Homo sapiens	49-52