PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22233829-10	2012	Significant correlations were found between estradiol and IL-10 in male patients, and between dehydroepiandrosterone (DHEA) and IL-1beta, and androstenedione and IL-17 in female patients.	Estradiol	44-53	interleukin 10	Homo sapiens	58-63	
27317920-0	2016	Progesterone and estradiol exert an inhibitory effect on the production of anti-inflammatory cytokine IL-10 by activated MZ B cells.	Estradiol	17-26	interleukin 10	Homo sapiens	102-107	
23733877-6	2013	Furthermore, we show that maternal serum IL-10 levels correlate with serum estradiol and estriol, implicating hormonal involvement in this alignment.	Estradiol	75-84	interleukin 10	Homo sapiens	41-46	
23422356-6	2013	In the third phase of gestation (41-57 days), an increase in IL-10 occurs, which might depend on high levels of 17beta-estradiol that, during pregnancy, interfere with the ability of dendritic cells to stimulate T lymphocytes, acting as an anti-inflammatory factor.	Estradiol	112-128	interleukin 10	Homo sapiens	61-66	
14523355-4	2003	RESULTS: At preovulatory concentrations, estradiol enhanced significantly IFN-gamma, IL-12 and IL-10, but not TNF-alpha, production levels and reversed the suppressive effect of hydrocortisone in PHA+LPS stimulated whole blood.	Estradiol	41-50	interleukin 10	Homo sapiens	95-100	
17348820-5	2007	Beta-estradiol levels in women with primary infections showed significant negative correlations with cervical concentrations of IL-10, IL-1beta, and IL-6.	Estradiol	0-14	interleukin 10	Homo sapiens	128-133	
15349790-4	2004	The recent demonstration that the female hormone, 17beta-estradiol prevents UVR-induced suppression of the contact hypersensitivity response caused by the release of immunosuppressive cytokines (IL-10) from keratinocytes might thus explain why the risk of PLE is higher in females than in males and why the risk decreases in women after the menopause.	Estradiol	50-66	interleukin 10	Homo sapiens	195-200	
21200384-5	2011	Treatment of BMC and Treg cell cocultures with 17beta-estradiol (E2) at concentrations between 10-7 and 10-9 mol/l suppressed OC differentiation and bone resorption more efficiently than it did in cultures of BMCs alone; this enhanced suppression occurred via the stimulation of Treg cell IL-10 and TGF-beta1 expression.	Estradiol	47-63	interleukin 10	Homo sapiens	289-294	
16154043-7	2005	RESULTS: Incubation with progesterone or estradiol resulted in a significant upregulation of IL-10 production by iDC and mDC.	Estradiol	41-50	interleukin 10	Homo sapiens	93-98	
16557037-7	2005	Higher prolactin levels as in pregnancy did not modulate any of the cytokines, but pregnancy estradiol concentrations only induced higher IL-10 levels in PHA + LPS-stimulated whole blood.	Estradiol	93-102	interleukin 10	Homo sapiens	138-143	
11788177-13	2001	Therefore, we assume that IL-10 has a role in OHSS as a local mediator of inflammation, however, it presents different aspects of the OHSS than the sex steroids 17beta-estradiol and progesterone.	Estradiol	161-177	interleukin 10	Homo sapiens	26-31	
9949320-11	1999	Anti-IL-10 antibody partially blocked the E2 effect on immunoglobulin production of PBMCs; anti-IL-10 reduced IgG production in the presence of E2 from 206% to 154% of control cells, and that of IgM from 206% to 152%.	Estradiol	42-44	interleukin 10	Homo sapiens	5-10	
9581884-11	1998	Peak interleukin 10 (40 pg/ml) levels corresponded precisely with estradiol peak levels just before ovulation.	Estradiol	66-75	interleukin 10	Homo sapiens	5-19	
32311377-11	2020	E2 reduced the negative impact of menopause and aging on insulin sensitivity by favoring increase in the level of IL-10 and decrease in the levels of TNF-alpha and IL-1beta.	Estradiol	0-2	interleukin 10	Homo sapiens	114-119	
9083615-1	1997	PROBLEM: The present study aimed at investigating the presence of Interleukin-10 (IL-10) in preovulatory follicular fluid (FF) and its possible correlation with 17-beta-estradiol (E2) and progesterone (P) levels, and treatment outcome in patients undergoing in-vitro fertilization-embryo transfer (IVF-ET).	Estradiol	161-178	interleukin 10	Homo sapiens	66-80	
9083615-1	1997	PROBLEM: The present study aimed at investigating the presence of Interleukin-10 (IL-10) in preovulatory follicular fluid (FF) and its possible correlation with 17-beta-estradiol (E2) and progesterone (P) levels, and treatment outcome in patients undergoing in-vitro fertilization-embryo transfer (IVF-ET).	Estradiol	161-178	interleukin 10	Homo sapiens	82-87