PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26243545-6	2016	Incubation of cells with 10(-8) mol/L 17beta-estradiol induced a time-dependent increase in PR-A and PR-B messenger RNAs (mRNAs) by quantitative real-time polymerase chain reactions and proteins by immunoblotting and immunofluorescence.	Estradiol	38-54	S100 calcium binding protein A6	Homo sapiens	92-96	
21809103-1	2011	Estradiol and progesterone mediate their actions by binding to classical nuclear receptors, estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta) and progesterone receptor A and B (PR-A and PR-B) and the non-classical G protein-coupled estrogen receptor (GPER).	Estradiol	0-9	S100 calcium binding protein A6	Homo sapiens	197-201	
21372145-1	2011	Our laboratory has previously cloned and purified an ovarian protein found to be a novel 17beta-hydroxysteroid dehydrogenase type 7 enzyme (HSD17B7) (formerly prolactin receptor-associated protein) that converts the weak estrogen, estrone, to the highly potent estradiol.	Estradiol	261-270	S100 calcium binding protein A6	Homo sapiens	159-196	
9632845-10	1998	It was shown that beta-estradiol induced both PRa and PRb promoter activity in all of the osteosarcoma cell lines examined.	Estradiol	18-32	S100 calcium binding protein A6	Homo sapiens	46-49	
21918635-11	2011	We found that estrogens, including estradiol and estrone, had a higher affinity for hPR A and B monomers in comparison with the dimer, hPR AB, and that of the endogenous progesterone ligand.	Estradiol	35-44	S100 calcium binding protein A6	Homo sapiens	84-95	
15806153-4	2005	Treatment of HOSE or OCa cells with estrone or 17beta-estradiol at 10(-8) M for a period of 72 h induced significant loss of PR-A and PR-B mRNA and protein expression, with the regulation primarily controlled at the transcriptional level.	Estradiol	47-63	S100 calcium binding protein A6	Homo sapiens	125-129	
10732327-11	2000	Liganded PR-A and PR-B can each suppress estradiol-stimulated ER activity, with the magnitude of repression dependent on the PR isoform, progestin ligand, promoter, and cell type.	Estradiol	41-50	S100 calcium binding protein A6	Homo sapiens	9-13	
8788178-10	1996	Liganded PR-A and PR-B can each suppress estradiol-stimulated ER activity, with the magnitude of repression dependent on the PR isoform, progestin ligand, promoter, and cell type.	Estradiol	41-50	S100 calcium binding protein A6	Homo sapiens	9-13