PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35589416-6	2022	The suppressive effect of estradiol on the production of IL-1beta and IL-17A was abolished in mice lacking estrogen receptors in neutrophils and macrophages (Esr1f/fEsr2f/fLysM-Cre+ mice).	Estradiol	26-35	interleukin 17A	Mus musculus	70-76	
35589416-5	2022	RESULTS: Mice without endogenous ovarian hormones exhibited exacerbated psoriatic inflammation including increased production of IL-17A and IL-1beta, which was reversed by exogenously added estradiol.	Estradiol	190-199	interleukin 17A	Mus musculus	129-135	
30355939-10	2018	RESULTS: The mice treated with either estradiol or oil had presented to us lowered levels in miR-1192 expression as well as higher levels in both Th17 cell percentage and expression of RORgammat in Th17 cells, along with mRNA and protein expressions of CXCR4, IL-6, IL-17, and IL-23.	Estradiol	38-47	interleukin 17A	Mus musculus	266-271	
33028712-9	2020	Finally, the enhanced vaginal Th1 TRM cells present in E2-treated mice were found to be modulated through an IL-17-mediated pathway, as E2-treated IL-17A deficient mice had impaired establishment of Th1 TRM cells.	Estradiol	55-57	interleukin 17A	Mus musculus	109-114	
33028712-9	2020	Finally, the enhanced vaginal Th1 TRM cells present in E2-treated mice were found to be modulated through an IL-17-mediated pathway, as E2-treated IL-17A deficient mice had impaired establishment of Th1 TRM cells.	Estradiol	55-57	interleukin 17A	Mus musculus	147-153	
29654199-8	2018	Estradiol supplementation or IL-17A inhibition decreased the number of ruptures in estrogen-deficient mice (estradiol 6% versus 37%; P=0.04; IL-17A inhibition 18% versus 47%; P=0.018).	Estradiol	0-9	interleukin 17A	Mus musculus	141-147	
29654199-8	2018	Estradiol supplementation or IL-17A inhibition decreased the number of ruptures in estrogen-deficient mice (estradiol 6% versus 37%; P=0.04; IL-17A inhibition 18% versus 47%; P=0.018).	Estradiol	108-117	interleukin 17A	Mus musculus	29-35	
33028712-9	2020	Finally, the enhanced vaginal Th1 TRM cells present in E2-treated mice were found to be modulated through an IL-17-mediated pathway, as E2-treated IL-17A deficient mice had impaired establishment of Th1 TRM cells.	Estradiol	136-138	interleukin 17A	Mus musculus	109-114	
33028712-9	2020	Finally, the enhanced vaginal Th1 TRM cells present in E2-treated mice were found to be modulated through an IL-17-mediated pathway, as E2-treated IL-17A deficient mice had impaired establishment of Th1 TRM cells.	Estradiol	136-138	interleukin 17A	Mus musculus	147-153	
31849948-2	2019	While estradiol and progesterone increased IL-17A production in Th17 cells by inhibiting Let7f miRNA expression and increasing IL-23 receptor (IL-23R) expression, it remained unclear how estrogen signaling through the canonical nuclear receptors, estrogen receptor alpha (ERalpha) and/or ERbeta, regulated this pathway.	Estradiol	6-15	interleukin 17A	Mus musculus	43-49	
31356161-0	2019	IL-17 Production by gammadelta+ T Cells Is Critical for Inducing Th17 Responses in the Female Genital Tract and Regulated by Estradiol and Microbiota.	Estradiol	125-134	interleukin 17A	Mus musculus	0-5