PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33523841-6	2021	Deficiency of NLRP3 also reduced serum FSH and estradiol levels.	Estradiol	47-56	NLR family pyrin domain containing 3	Homo sapiens	14-19	
34524457-5	2021	NLRP3 is highly expressed during the mid-proliferative and mid-secretory phases of the human endometrium and transcriptionally up-regulated by estradiol (E2) through estrogen receptor beta (ERbeta).	Estradiol	143-152	NLR family pyrin domain containing 3	Homo sapiens	0-5	
34524457-5	2021	NLRP3 is highly expressed during the mid-proliferative and mid-secretory phases of the human endometrium and transcriptionally up-regulated by estradiol (E2) through estrogen receptor beta (ERbeta).	Estradiol	154-156	NLR family pyrin domain containing 3	Homo sapiens	0-5	
34524457-7	2021	Our findings suggest that NLRP3, which is transcriptionally regulated by E2, induces epithelial-mesenchymal transition of endometrial epithelial cells and promotes embryo adhesion.	Estradiol	73-75	NLR family pyrin domain containing 3	Homo sapiens	26-31	
29105345-0	2018	Estradiol inhibits NLRP3 inflammasome in fibroblast-like synoviocytes activated by lipopolysaccharide and adenosine triphosphate.	Estradiol	0-9	NLR family pyrin domain containing 3	Homo sapiens	19-24	
26006022-8	2015	Our data reveal that treatment with 17beta-estradiol (E2) significantly inhibited the malignant behavior of HCC cells through E2/ERbeta/MAPK pathway-mediated upregulation of the NLRP3 inflammasome.	Estradiol	36-52	NLR family pyrin domain containing 3	Homo sapiens	178-183