PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19010312-13 2009 Using known structure-activity relationships for the inhibition of PGHS-1 and PGHS-2 by indole acetic acids we obtained N-(4-chlorobenzoyl)-melatonin as a specific AKR1C3 inhibitor (K(I)=6.0muM) that does not inhibit PGHS-1, PGHS-2, AKR1C1, or AKR1C2. N-(4-chlorobenzoyl)melatonin 120-149 prostaglandin-endoperoxide synthase 1 Homo sapiens 67-73 19010312-13 2009 Using known structure-activity relationships for the inhibition of PGHS-1 and PGHS-2 by indole acetic acids we obtained N-(4-chlorobenzoyl)-melatonin as a specific AKR1C3 inhibitor (K(I)=6.0muM) that does not inhibit PGHS-1, PGHS-2, AKR1C1, or AKR1C2. N-(4-chlorobenzoyl)melatonin 120-149 prostaglandin-endoperoxide synthase 1 Homo sapiens 217-223