PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2468125-4 1989 Differentiated BC3H-1 monocytes showed an approximate twofold elevation in the [32P] content of pp60c-src following stimulation with insulin or TPA for 20 min, with no detectable change in the level of immunoprecipitable c-src protein. Tetradecanoylphorbol Acetate 144-147 Rous sarcoma oncogene Mus musculus 96-105 2474754-1 1989 The product of the c-src proto-oncogene, pp60c-src, is phosphorylated at Ser-17 by cyclic AMP-dependent protein kinase A and at Ser-12 by calcium-phospholipid-dependent protein kinase C (when stimulated by 12-O-tetradecanoyl phorbol acetate). Tetradecanoylphorbol Acetate 206-240 Rous sarcoma oncogene Mus musculus 21-24 2474754-1 1989 The product of the c-src proto-oncogene, pp60c-src, is phosphorylated at Ser-17 by cyclic AMP-dependent protein kinase A and at Ser-12 by calcium-phospholipid-dependent protein kinase C (when stimulated by 12-O-tetradecanoyl phorbol acetate). Tetradecanoylphorbol Acetate 206-240 Rous sarcoma oncogene Mus musculus 41-50 2468125-8 1989 In cells exposed to high concentrations of TPA for 16 h to deplete PK-C activity, insulin, but not TPA, stimulated phosphorylation of pp60c-src. Tetradecanoylphorbol Acetate 43-46 Rous sarcoma oncogene Mus musculus 134-143 7557381-4 1995 A second tyrosine kinase activity is induced in response to both calcium and TPA, and has been identified as fyn, a nonreceptor tyrosine kinase of the src family. Tetradecanoylphorbol Acetate 77-80 Rous sarcoma oncogene Mus musculus 151-154 26100520-4 2015 The combination of ursolic acid + resveratrol inhibited TPA-induced signaling pathways, including EGFR, STAT3, Src, Akt, Cox-2, Fas, NF-kappaB, p38 MAPK, c-Jun, and JNK1/2 while increasing levels of tumor suppressors, such as p21 and PDCD4, to a greater extent compared with the groups treated with the individual compounds. Tetradecanoylphorbol Acetate 56-59 Rous sarcoma oncogene Mus musculus 111-114 22586143-4 2012 In a phorbol 12-myristate 13-acetate (PMA)-stimulated pituitary adenoma cell line, AtT-20 cells, we found that the cleavage of L1 was correspondingly enhanced with the increased interaction between Src and Shc. Tetradecanoylphorbol Acetate 5-36 Rous sarcoma oncogene Mus musculus 198-201 22586143-4 2012 In a phorbol 12-myristate 13-acetate (PMA)-stimulated pituitary adenoma cell line, AtT-20 cells, we found that the cleavage of L1 was correspondingly enhanced with the increased interaction between Src and Shc. Tetradecanoylphorbol Acetate 38-41 Rous sarcoma oncogene Mus musculus 198-201 7557381-6 1995 Cortactin, a p80-85 substrate of src- and fyn-related kinases that localizes with actin at cell adhesion sites, is increasingly tyrosine phosphorylated in calcium- and TPA-induced differentiation, with a time course which parallels that of fyn activation. Tetradecanoylphorbol Acetate 168-171 Rous sarcoma oncogene Mus musculus 33-36 2115120-5 1990 Cotransfection experiments using separate v-src and neo plasmids revealed a decrease in the number of G418-resistant colonies when transfections of TNR9 cells occurred in the presence of the src-containing plasmid, suggesting a growth inhibitory effect of v-src on 3T3-TNR9 cells, as has also been found for TPA itself. Tetradecanoylphorbol Acetate 308-311 Rous sarcoma oncogene Mus musculus 191-194 2115120-5 1990 Cotransfection experiments using separate v-src and neo plasmids revealed a decrease in the number of G418-resistant colonies when transfections of TNR9 cells occurred in the presence of the src-containing plasmid, suggesting a growth inhibitory effect of v-src on 3T3-TNR9 cells, as has also been found for TPA itself. Tetradecanoylphorbol Acetate 308-311 Rous sarcoma oncogene Mus musculus 191-194 2067850-2 1991 Depleting cells of protein kinase C (PKC) by prolonged exposure to 12-O-tetradecanoylphorbol 13-acetate (TPA), blocked v-Src-induced TIS10 expression, but had no effect on v-Src-induced Egr-1 gene expression. Tetradecanoylphorbol Acetate 105-108 Rous sarcoma oncogene Mus musculus 121-124